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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BICD2
All Species:
36.06
Human Site:
S681
Identified Species:
66.11
UniProt:
Q8TD16
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD16
NP_001003800.1
824
93533
S681
E
E
I
L
K
L
K
S
L
L
S
T
K
R
E
Chimpanzee
Pan troglodytes
XP_520695
824
93543
S681
E
E
I
L
K
L
K
S
L
L
S
T
K
R
E
Rhesus Macaque
Macaca mulatta
XP_001103849
824
93513
S681
E
E
I
L
K
L
K
S
L
L
S
T
K
R
E
Dog
Lupus familis
XP_541330
836
94592
S662
E
E
I
L
K
L
K
S
L
L
S
T
K
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q921C5
820
93372
S677
E
E
I
L
K
L
K
S
L
L
S
T
K
R
E
Rat
Rattus norvegicus
NP_001028846
851
96691
S677
E
E
I
L
K
L
K
S
L
L
S
T
K
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508342
737
84371
N600
N
L
K
S
K
Y
E
N
E
K
A
M
V
T
E
Chicken
Gallus gallus
XP_414332
815
93688
S672
E
E
I
L
K
L
K
S
L
L
S
T
K
R
E
Frog
Xenopus laevis
NP_001089257
656
76176
K519
G
S
K
L
H
F
R
K
R
K
S
S
D
F
F
Zebra Danio
Brachydanio rerio
XP_685529
809
92084
S655
E
E
I
L
K
L
K
S
L
L
S
T
K
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16568
782
88935
S622
E
Q
I
V
K
L
K
S
L
L
S
V
K
R
E
Honey Bee
Apis mellifera
XP_396412
766
87933
A610
E
Q
V
I
R
L
K
A
L
L
S
A
K
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798054
762
88207
G622
D
E
V
V
Q
L
K
G
L
L
M
T
K
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.7
89.5
N.A.
94.9
91.1
N.A.
70
82.6
39.2
67.4
N.A.
39.3
39.8
N.A.
39.4
Protein Similarity:
100
99.8
99
92.1
N.A.
96.5
93.1
N.A.
79
91.1
56.6
80.3
N.A.
59
58.7
N.A.
60.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
13.3
100
N.A.
80
60
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
100
26.6
100
N.A.
93.3
93.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
77
70
0
0
0
0
8
0
8
0
0
0
0
0
93
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% F
% Gly:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
70
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
16
0
77
0
85
8
0
16
0
0
85
0
0
% K
% Leu:
0
8
0
70
0
85
0
0
85
85
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
8
0
8
0
0
0
0
85
0
% R
% Ser:
0
8
0
8
0
0
0
70
0
0
85
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
70
0
8
0
% T
% Val:
0
0
16
16
0
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _