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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BICD2
All Species:
26.06
Human Site:
Y557
Identified Species:
47.78
UniProt:
Q8TD16
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD16
NP_001003800.1
824
93533
Y557
N
R
V
M
L
D
Y
Y
R
E
G
Q
G
G
A
Chimpanzee
Pan troglodytes
XP_520695
824
93543
Y557
N
R
V
M
L
D
Y
Y
R
E
G
Q
G
G
A
Rhesus Macaque
Macaca mulatta
XP_001103849
824
93513
Y557
N
R
V
M
L
D
Y
Y
R
E
G
Q
G
G
A
Dog
Lupus familis
XP_541330
836
94592
Y550
T
R
V
V
L
D
Y
Y
R
E
G
P
A
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q921C5
820
93372
Y559
N
R
V
M
L
D
Y
Y
R
E
G
Q
G
K
A
Rat
Rattus norvegicus
NP_001028846
851
96691
Y559
N
R
V
M
L
D
Y
Y
R
E
G
Q
G
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508342
737
84371
S494
E
S
T
P
S
P
V
S
S
L
P
S
P
I
S
Chicken
Gallus gallus
XP_414332
815
93688
Y556
N
R
V
M
L
D
Y
Y
K
E
G
K
G
G
R
Frog
Xenopus laevis
NP_001089257
656
76176
F413
A
L
Q
Q
Y
Q
N
F
K
K
K
Y
K
E
E
Zebra Danio
Brachydanio rerio
XP_685529
809
92084
P546
C
M
C
N
N
E
T
P
N
R
V
M
L
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16568
782
88935
T516
T
V
N
G
E
T
P
T
R
V
L
L
D
H
K
Honey Bee
Apis mellifera
XP_396412
766
87933
E501
H
V
C
T
V
N
G
E
I
P
S
R
V
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798054
762
88207
L512
N
R
I
M
Q
D
H
L
K
V
T
R
Q
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.7
89.5
N.A.
94.9
91.1
N.A.
70
82.6
39.2
67.4
N.A.
39.3
39.8
N.A.
39.4
Protein Similarity:
100
99.8
99
92.1
N.A.
96.5
93.1
N.A.
79
91.1
56.6
80.3
N.A.
59
58.7
N.A.
60.1
P-Site Identity:
100
100
100
73.3
N.A.
93.3
93.3
N.A.
0
80
0
0
N.A.
6.6
0
N.A.
26.6
P-Site Similarity:
100
100
100
80
N.A.
93.3
93.3
N.A.
6.6
93.3
20
6.6
N.A.
6.6
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
47
% A
% Cys:
8
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
62
0
0
0
0
0
0
8
8
0
% D
% Glu:
8
0
0
0
8
8
0
8
0
54
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
8
0
0
8
0
0
0
54
0
47
39
0
% G
% His:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
24
8
8
8
8
16
8
% K
% Leu:
0
8
0
0
54
0
0
8
0
8
8
8
8
0
8
% L
% Met:
0
8
0
54
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
54
0
8
8
8
8
8
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
8
8
8
0
8
8
8
8
0
0
% P
% Gln:
0
0
8
8
8
8
0
0
0
0
0
39
8
0
0
% Q
% Arg:
0
62
0
0
0
0
0
0
54
8
0
16
0
0
16
% R
% Ser:
0
8
0
0
8
0
0
8
8
0
8
8
0
8
8
% S
% Thr:
16
0
8
8
0
8
8
8
0
0
8
0
0
0
0
% T
% Val:
0
16
54
8
8
0
8
0
0
16
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
54
54
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _