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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF398 All Species: 9.09
Human Site: Y257 Identified Species: 33.33
UniProt: Q8TD17 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TD17 NP_065832.1 642 71311 Y257 S D V Y K S T Y A D E E L V I
Chimpanzee Pan troglodytes XP_001166485 642 71262 Y257 S D V Y K S T Y A D E E L V I
Rhesus Macaque Macaca mulatta XP_001095994 831 93844 S433 T E G S S E F S E L K Q M L V
Dog Lupus familis XP_539902 925 103521 S527 T E G S S E F S E L K Q M L V
Cat Felis silvestris
Mouse Mus musculus Q3U133 652 69772 S262 D L P P H H P S S A C S D G T
Rat Rattus norvegicus NP_001102700 643 71599 A258 E L Y K G T Y A D E E L V I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232215 513 58228 G134 W I L R L P P G A K G E V P K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 32 29.5 N.A. 37.5 91.7 N.A. N.A. 38 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 43 39.2 N.A. 48.3 95 N.A. N.A. 50.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 0 N.A. 0 6.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 46.6 46.6 N.A. 6.6 33.3 N.A. N.A. 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 15 43 15 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % C
% Asp: 15 29 0 0 0 0 0 0 15 29 0 0 15 0 0 % D
% Glu: 15 29 0 0 0 29 0 0 29 15 43 43 0 0 0 % E
% Phe: 0 0 0 0 0 0 29 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 29 0 15 0 0 15 0 0 15 0 0 15 0 % G
% His: 0 0 0 0 15 15 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 0 0 0 0 0 0 0 0 0 15 29 % I
% Lys: 0 0 0 15 29 0 0 0 0 15 29 0 0 0 29 % K
% Leu: 0 29 15 0 15 0 0 0 0 29 0 15 29 29 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 29 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 15 15 0 15 29 0 0 0 0 0 0 15 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 29 0 0 0 % Q
% Arg: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 29 0 0 29 29 29 0 43 15 0 0 15 0 0 0 % S
% Thr: 29 0 0 0 0 15 29 0 0 0 0 0 0 0 15 % T
% Val: 0 0 29 0 0 0 0 0 0 0 0 0 29 29 29 % V
% Trp: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 15 29 0 0 15 29 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _