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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS4Y2
All Species:
42.12
Human Site:
Y121
Identified Species:
66.19
UniProt:
Q8TD47
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD47
NP_001034656.1
263
29295
Y121
I
T
V
E
E
A
K
Y
K
L
C
K
V
R
K
Chimpanzee
Pan troglodytes
Q6GVM7
263
29340
Y121
I
T
V
E
E
A
K
Y
K
L
C
K
V
R
K
Rhesus Macaque
Macaca mulatta
NP_001138538
263
29372
Y121
I
T
A
E
E
A
K
Y
K
L
C
K
V
R
K
Dog
Lupus familis
XP_537399
267
29962
Y121
I
T
P
E
E
A
K
Y
K
L
C
K
V
R
K
Cat
Felis silvestris
Mouse
Mus musculus
XP_897768
255
28828
Y114
I
T
P
E
E
A
K
Y
K
L
C
K
V
R
K
Rat
Rattus norvegicus
NP_001103082
262
29180
Y121
I
T
P
E
E
A
K
Y
K
L
C
K
V
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510806
239
27018
M96
I
T
Y
P
A
G
F
M
D
V
I
S
I
E
K
Chicken
Gallus gallus
P47836
263
29576
Y121
I
T
A
E
E
A
K
Y
K
L
C
K
V
R
K
Frog
Xenopus laevis
P49401
263
29646
Y121
I
T
S
E
E
A
K
Y
K
L
C
K
V
R
K
Zebra Danio
Brachydanio rerio
Q642H9
263
29669
Y121
I
T
N
E
E
A
K
Y
K
L
C
K
V
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41042
261
29116
Y121
I
S
A
E
E
A
K
Y
K
L
C
K
V
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N3X2
259
29025
F120
I
Q
A
A
E
A
D
F
K
L
C
K
V
K
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O22424
265
29999
F121
I
R
D
E
D
A
K
F
K
L
C
K
V
R
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VYK6
262
29797
F121
I
K
D
E
E
A
K
F
K
L
C
K
V
R
S
Baker's Yeast
Sacchar. cerevisiae
P05753
261
29392
Y121
I
T
D
E
E
A
S
Y
K
L
G
K
V
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
94.6
89.5
N.A.
76.8
86.3
N.A.
80.2
92.7
92
87
N.A.
71.4
N.A.
60.8
N.A.
Protein Similarity:
100
98.8
97.7
94.3
N.A.
85.5
92.7
N.A.
83.6
95.8
95.4
93.9
N.A.
85.9
N.A.
76
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
20
93.3
93.3
93.3
N.A.
80
N.A.
53.3
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
33.3
93.3
93.3
93.3
N.A.
93.3
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
65.2
N.A.
65
67.6
N.A.
Protein Similarity:
N.A.
78.8
N.A.
79
81.7
N.A.
P-Site Identity:
N.A.
66.6
N.A.
73.3
73.3
N.A.
P-Site Similarity:
N.A.
80
N.A.
80
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
27
7
7
94
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
87
0
0
0
0
% C
% Asp:
0
0
20
0
7
0
7
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
0
87
87
0
0
0
0
0
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
7
20
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
100
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% I
% Lys:
0
7
0
0
0
0
80
0
94
0
0
94
0
20
80
% K
% Leu:
0
0
0
0
0
0
0
0
0
94
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
20
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
0
0
0
0
0
0
0
0
0
74
0
% R
% Ser:
0
7
7
0
0
0
7
0
0
0
0
7
0
0
20
% S
% Thr:
0
74
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
14
0
0
0
0
0
0
7
0
0
94
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
74
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _