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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLEKHO2 All Species: 17.58
Human Site: S29 Identified Species: 48.33
UniProt: Q8TD55 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TD55 NP_079477.2 490 53350 S29 A G W I K K S S G G L L G F W
Chimpanzee Pan troglodytes XP_523099 680 74369 S219 A G W I K K S S G G L L G F W
Rhesus Macaque Macaca mulatta XP_001101743 625 67750 S164 A G W I K K S S G G L L G F W
Dog Lupus familis XP_544722 498 54274 S29 A G W I K K S S G G L L G L W
Cat Felis silvestris
Mouse Mus musculus Q8K124 495 53854 S29 A G W I K K S S G G L L G L W
Rat Rattus norvegicus Q5BJM5 408 46049
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509868 315 32289
Chicken Gallus gallus Q5F3C8 423 48133
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A4IG55 520 58733 I35 R R F S G K G I F R E I W R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72 75.3 81.5 N.A. 76.9 29.5 N.A. 24.8 27.3 N.A. 26.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 72 76 85.3 N.A. 83.4 45.7 N.A. 35.5 43.6 N.A. 44.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 0 N.A. 0 0 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 0 N.A. 0 0 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % E
% Phe: 0 0 12 0 0 0 0 0 12 0 0 0 0 34 0 % F
% Gly: 0 56 0 0 12 0 12 0 56 56 0 0 56 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 56 0 0 0 12 0 0 0 12 0 0 0 % I
% Lys: 0 0 0 0 56 67 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 56 56 0 23 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 12 12 0 0 0 0 0 0 0 12 0 0 0 12 0 % R
% Ser: 0 0 0 12 0 0 56 56 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 56 0 0 0 0 0 0 0 0 0 12 0 56 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _