KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHO2
All Species:
8.79
Human Site:
S318
Identified Species:
24.17
UniProt:
Q8TD55
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD55
NP_079477.2
490
53350
S318
T
P
P
P
K
I
L
S
E
K
L
K
A
S
M
Chimpanzee
Pan troglodytes
XP_523099
680
74369
S508
T
P
P
P
K
I
L
S
E
K
L
K
A
S
M
Rhesus Macaque
Macaca mulatta
XP_001101743
625
67750
S453
T
P
P
P
K
I
L
S
E
K
L
K
A
C
M
Dog
Lupus familis
XP_544722
498
54274
E318
P
P
P
K
I
L
S
E
K
L
R
A
S
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K124
495
53854
M319
P
K
I
L
S
E
K
M
K
A
C
M
S
G
V
Rat
Rattus norvegicus
Q5BJM5
408
46049
W243
A
S
S
L
S
R
P
W
E
R
P
D
K
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509868
315
32289
D149
A
P
E
T
L
R
D
D
L
G
G
G
G
P
G
Chicken
Gallus gallus
Q5F3C8
423
48133
L258
P
T
Q
R
K
D
S
L
D
K
G
T
V
Y
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IG55
520
58733
R330
M
G
S
Y
P
Y
L
R
G
I
D
S
P
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72
75.3
81.5
N.A.
76.9
29.5
N.A.
24.8
27.3
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72
76
85.3
N.A.
83.4
45.7
N.A.
35.5
43.6
N.A.
44.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
0
6.6
N.A.
6.6
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
33.3
N.A.
20
13.3
N.A.
6.6
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
0
0
0
0
0
0
12
0
12
34
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% C
% Asp:
0
0
0
0
0
12
12
12
12
0
12
12
0
0
0
% D
% Glu:
0
0
12
0
0
12
0
12
45
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
0
0
12
12
23
12
12
23
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
12
34
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
12
0
12
45
0
12
0
23
45
0
34
12
0
0
% K
% Leu:
0
0
0
23
12
12
45
12
12
12
34
0
0
0
12
% L
% Met:
12
0
0
0
0
0
0
12
0
0
0
12
0
12
34
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
34
56
45
34
12
0
12
0
0
0
12
0
12
12
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
23
0
12
0
12
12
0
0
12
0
% R
% Ser:
0
12
23
0
23
0
23
34
0
0
0
12
23
23
12
% S
% Thr:
34
12
0
12
0
0
0
0
0
0
0
12
0
0
12
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
12
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _