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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX54 All Species: 35.76
Human Site: S440 Identified Species: 56.19
UniProt: Q8TDD1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDD1 NP_001104792.1 881 98595 S440 G R S G T A Y S L V A P D E I
Chimpanzee Pan troglodytes XP_001152281 884 99131 S440 G R S G T A Y S L V A P D E I
Rhesus Macaque Macaca mulatta XP_001111246 883 98886 S440 G R S G T A Y S L V V P D E I
Dog Lupus familis XP_850776 889 98892 S448 G R S G T A Y S L V A P D E V
Cat Felis silvestris
Mouse Mus musculus Q8K4L0 874 97729 S439 G R S G T A Y S L V A P D E V
Rat Rattus norvegicus XP_001079855 874 97768 S439 G R S G T A Y S L V A P D E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001088266 846 94831 S419 G R S G T A Y S F I A P D E I
Zebra Danio Brachydanio rerio NP_775375 862 97037 G418 V A R A G R G G T A Y S L V C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_612028 827 93352 L400 L L D L H L F L N R P F N I H
Honey Bee Apis mellifera XP_397101 743 84721 T377 A R A G R T G T A Y N I V S P
Nematode Worm Caenorhab. elegans NP_741348 825 93065 N389 M F L G K P I N F A S D K S E
Sea Urchin Strong. purpuratus XP_792708 889 98517 S417 G R T G T A Y S M V A P D E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49289 845 93485 D385 E D M P Y M L D L H L F L S K
Baker's Yeast Sacchar. cerevisiae Q12389 995 113139 S534 G N K G W A Y S I V A E N E L
Red Bread Mold Neurospora crassa Q7S9J4 934 103635 G476 G Q R G W A Y G L V R Q S D V
Conservation
Percent
Protein Identity: 100 98.9 96.8 86.8 N.A. 85.2 85.1 N.A. N.A. N.A. 63.3 60.7 N.A. 38.3 43.4 40.6 51.9
Protein Similarity: 100 99.3 97.8 91.5 N.A. 90.9 90.6 N.A. N.A. N.A. 76.6 74.6 N.A. 56.5 59.7 58.4 68.7
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. 86.6 0 N.A. 0 13.3 6.6 80
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. N.A. N.A. 93.3 0 N.A. 13.3 26.6 20 100
Percent
Protein Identity: N.A. N.A. N.A. 41.2 33.8 36
Protein Similarity: N.A. N.A. N.A. 58 50.1 55
P-Site Identity: N.A. N.A. N.A. 6.6 53.3 40
P-Site Similarity: N.A. N.A. N.A. 6.6 73.3 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 7 0 67 0 0 7 14 54 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 7 7 0 0 0 0 7 0 0 0 7 54 7 0 % D
% Glu: 7 0 0 0 0 0 0 0 0 0 0 7 0 60 7 % E
% Phe: 0 7 0 0 0 0 7 0 14 0 0 14 0 0 0 % F
% Gly: 67 0 0 80 7 0 14 14 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 0 7 0 7 7 0 7 0 7 27 % I
% Lys: 0 0 7 0 7 0 0 0 0 0 0 0 7 0 7 % K
% Leu: 7 7 7 7 0 7 7 7 54 0 7 0 14 0 14 % L
% Met: 7 0 7 0 0 7 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 7 7 0 7 0 14 0 0 % N
% Pro: 0 0 0 7 0 7 0 0 0 0 7 54 0 0 7 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 0 60 14 0 7 7 0 0 0 7 7 0 0 0 0 % R
% Ser: 0 0 47 0 0 0 0 60 0 0 7 7 7 20 0 % S
% Thr: 0 0 7 0 54 7 0 7 7 0 0 0 0 0 0 % T
% Val: 7 0 0 0 0 0 0 0 0 60 7 0 7 7 27 % V
% Trp: 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 67 0 0 7 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _