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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX54
All Species:
10.61
Human Site:
S493
Identified Species:
16.67
UniProt:
Q8TDD1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDD1
NP_001104792.1
881
98595
S493
S
V
V
D
E
E
D
S
G
L
Q
S
T
L
E
Chimpanzee
Pan troglodytes
XP_001152281
884
99131
S493
S
V
V
D
E
E
D
S
G
L
Q
S
T
L
E
Rhesus Macaque
Macaca mulatta
XP_001111246
883
98886
S493
S
V
V
D
E
E
D
S
G
L
Q
S
T
L
E
Dog
Lupus familis
XP_850776
889
98892
E501
P
Q
S
V
V
D
D
E
E
S
G
L
Q
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4L0
874
97729
E492
P
Q
S
V
V
D
D
E
D
S
S
L
Q
T
A
Rat
Rattus norvegicus
XP_001079855
874
97768
E492
P
Q
S
V
V
D
D
E
D
S
S
L
Q
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088266
846
94831
L472
L
I
D
D
E
D
A
L
L
I
T
D
R
E
R
Zebra Danio
Brachydanio rerio
NP_775375
862
97037
C471
S
V
L
D
D
E
E
C
Q
L
I
T
A
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_612028
827
93352
S453
A
Y
K
K
Y
L
S
S
R
P
V
A
S
T
D
Honey Bee
Apis mellifera
XP_397101
743
84721
V430
A
M
I
E
E
E
L
V
E
L
I
N
W
H
N
Nematode Worm
Caenorhab. elegans
NP_741348
825
93065
K442
K
A
T
N
A
M
M
K
Y
T
R
T
R
P
P
Sea Urchin
Strong. purpuratus
XP_792708
889
98517
V470
V
V
D
D
E
E
S
V
L
R
N
L
H
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49289
845
93485
N438
K
T
I
D
L
I
F
N
R
T
R
E
M
I
D
Baker's Yeast
Sacchar. cerevisiae
Q12389
995
113139
L587
Y
Q
F
Q
P
P
K
L
S
Y
T
K
R
L
V
Red Bread Mold
Neurospora crassa
Q7S9J4
934
103635
V529
V
D
V
N
I
E
W
V
E
K
A
L
K
E
S
Conservation
Percent
Protein Identity:
100
98.9
96.8
86.8
N.A.
85.2
85.1
N.A.
N.A.
N.A.
63.3
60.7
N.A.
38.3
43.4
40.6
51.9
Protein Similarity:
100
99.3
97.8
91.5
N.A.
90.9
90.6
N.A.
N.A.
N.A.
76.6
74.6
N.A.
56.5
59.7
58.4
68.7
P-Site Identity:
100
100
100
6.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
13.3
33.3
N.A.
6.6
20
0
26.6
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
N.A.
N.A.
33.3
66.6
N.A.
33.3
53.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
33.8
36
Protein Similarity:
N.A.
N.A.
N.A.
58
50.1
55
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
6.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
0
0
7
0
7
0
0
0
7
7
7
0
14
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
7
14
47
7
27
40
0
14
0
0
7
0
0
14
% D
% Glu:
0
0
0
7
40
47
7
20
20
0
0
7
0
14
20
% E
% Phe:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
20
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
14
0
% H
% Ile:
0
7
14
0
7
7
0
0
0
7
14
0
0
7
7
% I
% Lys:
14
0
7
7
0
0
7
7
0
7
0
7
7
7
0
% K
% Leu:
7
0
7
0
7
7
7
14
14
34
0
34
0
27
0
% L
% Met:
0
7
0
0
0
7
7
0
0
0
0
0
7
0
7
% M
% Asn:
0
0
0
14
0
0
0
7
0
0
7
7
0
0
7
% N
% Pro:
20
0
0
0
7
7
0
0
0
7
0
0
0
7
7
% P
% Gln:
0
27
0
7
0
0
0
0
7
0
20
0
20
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
14
7
14
0
20
0
7
% R
% Ser:
27
0
20
0
0
0
14
27
7
20
14
20
7
7
7
% S
% Thr:
0
7
7
0
0
0
0
0
0
14
14
14
20
20
0
% T
% Val:
14
34
27
20
20
0
0
20
0
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% W
% Tyr:
7
7
0
0
7
0
0
0
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _