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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX54 All Species: 49.09
Human Site: S527 Identified Species: 77.14
UniProt: Q8TDD1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDD1 NP_001104792.1 881 98595 S527 V R S R P A P S P E S I K R A
Chimpanzee Pan troglodytes XP_001152281 884 99131 S527 V R S R P A P S P E S I K R A
Rhesus Macaque Macaca mulatta XP_001111246 883 98886 S527 V R S R P A P S P E S I K R A
Dog Lupus familis XP_850776 889 98892 S537 V R S R P A P S P E S I K R A
Cat Felis silvestris
Mouse Mus musculus Q8K4L0 874 97729 S528 V R S R P A P S P E S I K R A
Rat Rattus norvegicus XP_001079855 874 97768 S528 L R S R P A P S P E S I K R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001088266 846 94831 S505 I K S R P T P S P E S I K R V
Zebra Danio Brachydanio rerio NP_775375 862 97037 S505 L K S R P V P S A E S I K R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_612028 827 93352 L486 F F T A A P V L A Q A A E A S
Honey Bee Apis mellifera XP_397101 743 84721 S464 I R S R P A A S S E S I K R V
Nematode Worm Caenorhab. elegans NP_741348 825 93065 F474 V E C A P H P F L K A D G D K
Sea Urchin Strong. purpuratus XP_792708 889 98517 S503 L R S R P L P S P A S V K R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49289 845 93485 S472 S K T K P S P S K E S I R R A
Baker's Yeast Sacchar. cerevisiae Q12389 995 113139 S642 Y R T R T S A S P E S L K R S
Red Bread Mold Neurospora crassa Q7S9J4 934 103635 S561 M K T R N S A S S Q S A K R A
Conservation
Percent
Protein Identity: 100 98.9 96.8 86.8 N.A. 85.2 85.1 N.A. N.A. N.A. 63.3 60.7 N.A. 38.3 43.4 40.6 51.9
Protein Similarity: 100 99.3 97.8 91.5 N.A. 90.9 90.6 N.A. N.A. N.A. 76.6 74.6 N.A. 56.5 59.7 58.4 68.7
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. N.A. 73.3 66.6 N.A. 0 73.3 20 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 86.6 86.6 N.A. 33.3 80 33.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 41.2 33.8 36
Protein Similarity: N.A. N.A. N.A. 58 50.1 55
P-Site Identity: N.A. N.A. N.A. 53.3 53.3 40
P-Site Similarity: N.A. N.A. N.A. 86.6 80 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 7 47 20 0 14 7 14 14 0 7 54 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % D
% Glu: 0 7 0 0 0 0 0 0 0 74 0 0 7 0 0 % E
% Phe: 7 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 14 0 0 0 0 0 0 0 0 0 0 67 0 0 0 % I
% Lys: 0 27 0 7 0 0 0 0 7 7 0 0 80 0 7 % K
% Leu: 20 0 0 0 0 7 0 7 7 0 0 7 0 0 0 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 80 7 74 0 60 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 % Q
% Arg: 0 60 0 80 0 0 0 0 0 0 0 0 7 87 0 % R
% Ser: 7 0 67 0 0 20 0 87 14 0 87 0 0 0 27 % S
% Thr: 0 0 27 0 7 7 0 0 0 0 0 0 0 0 0 % T
% Val: 40 0 0 0 0 7 7 0 0 0 0 7 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _