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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX54
All Species:
26.36
Human Site:
S743
Identified Species:
41.43
UniProt:
Q8TDD1
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDD1
NP_001104792.1
881
98595
S743
K
K
R
F
V
G
Q
S
G
Q
E
D
K
K
K
Chimpanzee
Pan troglodytes
XP_001152281
884
99131
S746
K
K
R
F
V
G
Q
S
G
Q
E
D
K
K
K
Rhesus Macaque
Macaca mulatta
XP_001111246
883
98886
S745
K
K
R
F
V
G
K
S
G
Q
E
D
K
K
K
Dog
Lupus familis
XP_850776
889
98892
S751
K
K
R
F
V
G
Q
S
G
Q
E
D
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4L0
874
97729
S735
K
K
R
F
V
G
Q
S
G
Q
E
D
K
K
K
Rat
Rattus norvegicus
XP_001079855
874
97768
S735
K
K
R
F
V
G
Q
S
G
Q
E
D
K
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088266
846
94831
G708
K
K
K
F
V
G
T
G
G
Q
E
D
K
K
K
Zebra Danio
Brachydanio rerio
NP_775375
862
97037
T717
K
K
R
F
V
R
D
T
G
K
E
D
K
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_612028
827
93352
V690
I
K
K
K
M
V
S
V
Q
D
P
R
A
N
K
Honey Bee
Apis mellifera
XP_397101
743
84721
K628
I
K
K
W
D
R
K
K
K
K
I
I
T
I
N
Nematode Worm
Caenorhab. elegans
NP_741348
825
93065
G674
K
Y
V
G
L
S
G
G
N
E
P
A
N
K
K
Sea Urchin
Strong. purpuratus
XP_792708
889
98517
G706
K
K
F
V
G
D
G
G
K
D
G
K
Q
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49289
845
93485
D670
Y
I
K
L
N
N
G
D
R
V
T
A
S
G
K
Baker's Yeast
Sacchar. cerevisiae
Q12389
995
113139
Q849
R
K
K
Y
V
N
T
Q
G
I
D
N
K
K
Y
Red Bread Mold
Neurospora crassa
Q7S9J4
934
103635
D798
V
A
V
A
N
D
E
D
G
S
K
G
A
K
M
Conservation
Percent
Protein Identity:
100
98.9
96.8
86.8
N.A.
85.2
85.1
N.A.
N.A.
N.A.
63.3
60.7
N.A.
38.3
43.4
40.6
51.9
Protein Similarity:
100
99.3
97.8
91.5
N.A.
90.9
90.6
N.A.
N.A.
N.A.
76.6
74.6
N.A.
56.5
59.7
58.4
68.7
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
N.A.
80
66.6
N.A.
13.3
6.6
20
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
86.6
80
N.A.
26.6
33.3
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
33.8
36
Protein Similarity:
N.A.
N.A.
N.A.
58
50.1
55
P-Site Identity:
N.A.
N.A.
N.A.
6.6
33.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
66.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
0
0
0
0
14
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
14
7
14
0
14
7
54
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
0
0
7
54
0
0
0
0
% E
% Phe:
0
0
7
54
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
7
47
20
20
67
0
7
7
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
14
7
0
0
0
0
0
0
0
7
7
7
0
7
0
% I
% Lys:
67
80
34
7
0
0
14
7
14
14
7
7
60
74
80
% K
% Leu:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
14
14
0
0
7
0
0
7
7
7
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
34
7
7
47
0
0
7
0
0
% Q
% Arg:
7
0
47
0
0
14
0
0
7
0
0
7
0
0
0
% R
% Ser:
0
0
0
0
0
7
7
40
0
7
0
0
7
0
0
% S
% Thr:
0
0
0
0
0
0
14
7
0
0
7
0
7
0
0
% T
% Val:
7
0
14
7
60
7
0
7
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
7
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _