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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX54 All Species: 43.64
Human Site: S755 Identified Species: 68.57
UniProt: Q8TDD1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDD1 NP_001104792.1 881 98595 S755 K K K I K T E S G R Y I S S S
Chimpanzee Pan troglodytes XP_001152281 884 99131 S758 K K K I K T E S G R Y I S S S
Rhesus Macaque Macaca mulatta XP_001111246 883 98886 S757 K K K I K T E S G R Y I N S S
Dog Lupus familis XP_850776 889 98892 S763 K K K I K T E S G R Y I S S S
Cat Felis silvestris
Mouse Mus musculus Q8K4L0 874 97729 S747 K K K I K T E S G R F I S S S
Rat Rattus norvegicus XP_001079855 874 97768 S747 K K K I K T E S G R F I S S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001088266 846 94831 S720 K K K I K T E S G R L I S S S
Zebra Danio Brachydanio rerio NP_775375 862 97037 E729 K H K K I R T E S G Q L I R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_612028 827 93352 S702 A N K I R T E S G A W I P A S
Honey Bee Apis mellifera XP_397101 743 84721 V640 T I N N E Q N V R K I R T E S
Nematode Worm Caenorhab. elegans NP_741348 825 93065 D686 N K K I R T E D G T W L P A S
Sea Urchin Strong. purpuratus XP_792708 889 98517 S718 Q K K I M T E S G K Y I S A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49289 845 93485 S682 S G K I K T E S G A K A T A K
Baker's Yeast Sacchar. cerevisiae Q12389 995 113139 S861 K K Y I I G E S G Q K I A A S
Red Bread Mold Neurospora crassa Q7S9J4 934 103635 S810 A K M I R G E S G V K I A A S
Conservation
Percent
Protein Identity: 100 98.9 96.8 86.8 N.A. 85.2 85.1 N.A. N.A. N.A. 63.3 60.7 N.A. 38.3 43.4 40.6 51.9
Protein Similarity: 100 99.3 97.8 91.5 N.A. 90.9 90.6 N.A. N.A. N.A. 76.6 74.6 N.A. 56.5 59.7 58.4 68.7
P-Site Identity: 100 100 93.3 100 N.A. 93.3 93.3 N.A. N.A. N.A. 93.3 13.3 N.A. 53.3 6.6 46.6 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 93.3 20 N.A. 73.3 26.6 73.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 41.2 33.8 36
Protein Similarity: N.A. N.A. N.A. 58 50.1 55
P-Site Identity: N.A. N.A. N.A. 46.6 53.3 46.6
P-Site Similarity: N.A. N.A. N.A. 60 73.3 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 0 0 0 0 0 0 14 0 7 14 40 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 7 0 87 7 0 0 0 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 % F
% Gly: 0 7 0 0 0 14 0 0 87 7 0 0 0 0 7 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 87 14 0 0 0 0 0 7 74 7 0 0 % I
% Lys: 60 74 80 7 54 0 0 0 0 14 20 0 0 0 7 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 7 14 0 0 0 % L
% Met: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 7 7 0 0 7 0 0 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % P
% Gln: 7 0 0 0 0 7 0 0 0 7 7 0 0 0 0 % Q
% Arg: 0 0 0 0 20 7 0 0 7 47 0 7 0 7 0 % R
% Ser: 7 0 0 0 0 0 0 80 7 0 0 0 47 47 87 % S
% Thr: 7 0 0 0 0 74 7 0 0 7 0 0 14 0 0 % T
% Val: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 34 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _