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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX54
All Species:
31.52
Human Site:
T437
Identified Species:
49.52
UniProt:
Q8TDD1
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDD1
NP_001104792.1
881
98595
T437
A
R
A
G
R
S
G
T
A
Y
S
L
V
A
P
Chimpanzee
Pan troglodytes
XP_001152281
884
99131
T437
A
R
A
G
R
S
G
T
A
Y
S
L
V
A
P
Rhesus Macaque
Macaca mulatta
XP_001111246
883
98886
T437
A
R
A
G
R
S
G
T
A
Y
S
L
V
V
P
Dog
Lupus familis
XP_850776
889
98892
T445
A
R
A
G
R
S
G
T
A
Y
S
L
V
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4L0
874
97729
T436
A
R
A
G
R
S
G
T
A
Y
S
L
V
A
P
Rat
Rattus norvegicus
XP_001079855
874
97768
T436
A
R
A
G
R
S
G
T
A
Y
S
L
V
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088266
846
94831
T416
A
R
A
G
R
S
G
T
A
Y
S
F
I
A
P
Zebra Danio
Brachydanio rerio
NP_775375
862
97037
G415
V
G
R
V
A
R
A
G
R
G
G
T
A
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_612028
827
93352
H397
T
A
H
L
L
D
L
H
L
F
L
N
R
P
F
Honey Bee
Apis mellifera
XP_397101
743
84721
R374
G
R
C
A
R
A
G
R
T
G
T
A
Y
N
I
Nematode Worm
Caenorhab. elegans
NP_741348
825
93065
K386
D
L
F
M
F
L
G
K
P
I
N
F
A
S
D
Sea Urchin
Strong. purpuratus
XP_792708
889
98517
T414
A
R
A
G
R
T
G
T
A
Y
S
M
V
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49289
845
93485
Y382
V
T
P
E
D
M
P
Y
M
L
D
L
H
L
F
Baker's Yeast
Sacchar. cerevisiae
Q12389
995
113139
W531
A
R
A
G
N
K
G
W
A
Y
S
I
V
A
E
Red Bread Mold
Neurospora crassa
Q7S9J4
934
103635
W473
A
R
A
G
Q
R
G
W
A
Y
G
L
V
R
Q
Conservation
Percent
Protein Identity:
100
98.9
96.8
86.8
N.A.
85.2
85.1
N.A.
N.A.
N.A.
63.3
60.7
N.A.
38.3
43.4
40.6
51.9
Protein Similarity:
100
99.3
97.8
91.5
N.A.
90.9
90.6
N.A.
N.A.
N.A.
76.6
74.6
N.A.
56.5
59.7
58.4
68.7
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
N.A.
86.6
0
N.A.
0
20
6.6
86.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
N.A.
93.3
0
N.A.
6.6
33.3
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
33.8
36
Protein Similarity:
N.A.
N.A.
N.A.
58
50.1
55
P-Site Identity:
N.A.
N.A.
N.A.
6.6
66.6
60
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
73.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
7
67
7
7
7
7
0
67
0
0
7
14
54
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
7
0
0
0
0
7
0
0
0
7
% D
% Glu:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
7
0
7
0
0
0
0
7
0
14
0
0
14
% F
% Gly:
7
7
0
67
0
0
80
7
0
14
14
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
7
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
7
7
0
7
% I
% Lys:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% K
% Leu:
0
7
0
7
7
7
7
0
7
7
7
54
0
7
0
% L
% Met:
0
0
0
7
0
7
0
0
7
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
7
7
0
7
0
% N
% Pro:
0
0
7
0
0
0
7
0
7
0
0
0
0
7
54
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
74
7
0
60
14
0
7
7
0
0
0
7
7
0
% R
% Ser:
0
0
0
0
0
47
0
0
0
0
60
0
0
7
7
% S
% Thr:
7
7
0
0
0
7
0
54
7
0
7
7
0
0
0
% T
% Val:
14
0
0
7
0
0
0
0
0
0
0
0
60
7
0
% V
% Trp:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
67
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _