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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX54
All Species:
16.97
Human Site:
T462
Identified Species:
26.67
UniProt:
Q8TDD1
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDD1
NP_001104792.1
881
98595
T462
L
F
L
G
R
S
L
T
L
A
R
P
L
K
E
Chimpanzee
Pan troglodytes
XP_001152281
884
99131
T462
L
F
L
G
R
S
L
T
L
A
R
P
L
K
E
Rhesus Macaque
Macaca mulatta
XP_001111246
883
98886
A462
L
F
L
G
R
S
L
A
L
A
R
P
L
E
D
Dog
Lupus familis
XP_850776
889
98892
T470
L
F
L
G
R
A
L
T
P
A
R
P
H
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4L0
874
97729
T461
L
F
L
G
R
S
V
T
L
A
R
P
C
E
E
Rat
Rattus norvegicus
XP_001079855
874
97768
T461
L
F
L
G
R
S
V
T
L
A
R
P
H
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088266
846
94831
K441
L
F
L
G
R
P
L
K
L
A
N
A
Q
N
I
Zebra Danio
Brachydanio rerio
NP_775375
862
97037
G440
Y
D
L
H
L
F
L
G
R
P
M
Q
L
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_612028
827
93352
E422
I
P
Q
D
L
L
E
E
E
H
L
T
V
T
D
Honey Bee
Apis mellifera
XP_397101
743
84721
R399
D
L
H
L
F
L
G
R
S
L
H
I
V
P
P
Nematode Worm
Caenorhab. elegans
NP_741348
825
93065
I411
I
G
R
V
P
D
S
I
V
S
L
E
T
E
F
Sea Urchin
Strong. purpuratus
XP_792708
889
98517
A439
L
F
L
G
K
D
I
A
F
F
K
N
D
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49289
845
93485
M407
E
D
E
V
L
K
N
M
E
E
V
M
T
K
T
Baker's Yeast
Sacchar. cerevisiae
Q12389
995
113139
L556
L
F
L
G
K
K
I
L
L
T
P
M
Y
D
S
Red Bread Mold
Neurospora crassa
Q7S9J4
934
103635
I498
L
F
L
G
R
K
L
I
I
G
H
D
Q
K
N
Conservation
Percent
Protein Identity:
100
98.9
96.8
86.8
N.A.
85.2
85.1
N.A.
N.A.
N.A.
63.3
60.7
N.A.
38.3
43.4
40.6
51.9
Protein Similarity:
100
99.3
97.8
91.5
N.A.
90.9
90.6
N.A.
N.A.
N.A.
76.6
74.6
N.A.
56.5
59.7
58.4
68.7
P-Site Identity:
100
100
80
73.3
N.A.
80
80
N.A.
N.A.
N.A.
53.3
20
N.A.
0
0
0
26.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
53.3
20
N.A.
20
6.6
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
33.8
36
Protein Similarity:
N.A.
N.A.
N.A.
58
50.1
55
P-Site Identity:
N.A.
N.A.
N.A.
6.6
33.3
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
46.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
14
0
47
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
14
0
7
0
14
0
0
0
0
0
7
7
14
14
% D
% Glu:
7
0
7
0
0
0
7
7
14
7
0
7
0
34
34
% E
% Phe:
0
67
0
0
7
7
0
0
7
7
0
0
0
0
7
% F
% Gly:
0
7
0
67
0
0
7
7
0
7
0
0
0
0
0
% G
% His:
0
0
7
7
0
0
0
0
0
7
14
0
14
0
7
% H
% Ile:
14
0
0
0
0
0
14
14
7
0
0
7
0
0
7
% I
% Lys:
0
0
0
0
14
20
0
7
0
0
7
0
0
27
7
% K
% Leu:
67
7
74
7
20
14
47
7
47
7
14
0
27
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
7
14
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
7
7
0
7
7
% N
% Pro:
0
7
0
0
7
7
0
0
7
7
7
40
0
7
7
% P
% Gln:
0
0
7
0
0
0
0
0
0
0
0
7
14
0
0
% Q
% Arg:
0
0
7
0
54
0
0
7
7
0
40
0
0
0
0
% R
% Ser:
0
0
0
0
0
34
7
0
7
7
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
0
34
0
7
0
7
14
7
7
% T
% Val:
0
0
0
14
0
0
14
0
7
0
7
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _