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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX54
All Species:
38.48
Human Site:
T753
Identified Species:
60.48
UniProt:
Q8TDD1
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDD1
NP_001104792.1
881
98595
T753
E
D
K
K
K
I
K
T
E
S
G
R
Y
I
S
Chimpanzee
Pan troglodytes
XP_001152281
884
99131
T756
E
D
K
K
K
I
K
T
E
S
G
R
Y
I
S
Rhesus Macaque
Macaca mulatta
XP_001111246
883
98886
T755
E
D
K
K
K
I
K
T
E
S
G
R
Y
I
N
Dog
Lupus familis
XP_850776
889
98892
T761
E
D
K
K
K
I
K
T
E
S
G
R
Y
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4L0
874
97729
T745
E
D
K
K
K
I
K
T
E
S
G
R
F
I
S
Rat
Rattus norvegicus
XP_001079855
874
97768
T745
E
D
K
K
K
I
K
T
E
S
G
R
F
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088266
846
94831
T718
E
D
K
K
K
I
K
T
E
S
G
R
L
I
S
Zebra Danio
Brachydanio rerio
NP_775375
862
97037
R727
E
D
K
H
K
K
I
R
T
E
S
G
Q
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_612028
827
93352
T700
P
R
A
N
K
I
R
T
E
S
G
A
W
I
P
Honey Bee
Apis mellifera
XP_397101
743
84721
Q638
I
I
T
I
N
N
E
Q
N
V
R
K
I
R
T
Nematode Worm
Caenorhab. elegans
NP_741348
825
93065
T684
P
A
N
K
K
I
R
T
E
D
G
T
W
L
P
Sea Urchin
Strong. purpuratus
XP_792708
889
98517
T716
G
K
Q
K
K
I
M
T
E
S
G
K
Y
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49289
845
93485
T680
T
A
S
G
K
I
K
T
E
S
G
A
K
A
T
Baker's Yeast
Sacchar. cerevisiae
Q12389
995
113139
G859
D
N
K
K
Y
I
I
G
E
S
G
Q
K
I
A
Red Bread Mold
Neurospora crassa
Q7S9J4
934
103635
G808
K
G
A
K
M
I
R
G
E
S
G
V
K
I
A
Conservation
Percent
Protein Identity:
100
98.9
96.8
86.8
N.A.
85.2
85.1
N.A.
N.A.
N.A.
63.3
60.7
N.A.
38.3
43.4
40.6
51.9
Protein Similarity:
100
99.3
97.8
91.5
N.A.
90.9
90.6
N.A.
N.A.
N.A.
76.6
74.6
N.A.
56.5
59.7
58.4
68.7
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
26.6
N.A.
46.6
0
40
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
93.3
33.3
N.A.
60
20
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
33.8
36
Protein Similarity:
N.A.
N.A.
N.A.
58
50.1
55
P-Site Identity:
N.A.
N.A.
N.A.
46.6
46.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
73.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
14
0
0
0
0
0
0
0
0
14
0
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
54
0
0
0
0
0
0
0
7
0
0
0
0
0
% D
% Glu:
54
0
0
0
0
0
7
0
87
7
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% F
% Gly:
7
7
0
7
0
0
0
14
0
0
87
7
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
7
0
87
14
0
0
0
0
0
7
74
7
% I
% Lys:
7
7
60
74
80
7
54
0
0
0
0
14
20
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
7
14
0
% L
% Met:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
7
7
7
0
0
7
0
0
0
0
0
7
% N
% Pro:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% P
% Gln:
0
0
7
0
0
0
0
7
0
0
0
7
7
0
0
% Q
% Arg:
0
7
0
0
0
0
20
7
0
0
7
47
0
7
0
% R
% Ser:
0
0
7
0
0
0
0
0
0
80
7
0
0
0
47
% S
% Thr:
7
0
7
0
0
0
0
74
7
0
0
7
0
0
14
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
34
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _