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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX54
All Species:
36.97
Human Site:
Y569
Identified Species:
58.1
UniProt:
Q8TDD1
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDD1
NP_001104792.1
881
98595
Y569
L
V
D
S
I
K
N
Y
R
S
R
A
T
I
F
Chimpanzee
Pan troglodytes
XP_001152281
884
99131
Y569
L
V
D
S
I
K
N
Y
R
S
R
A
T
I
F
Rhesus Macaque
Macaca mulatta
XP_001111246
883
98886
Y569
L
V
D
S
I
K
N
Y
R
S
R
A
T
I
F
Dog
Lupus familis
XP_850776
889
98892
Y579
L
V
D
S
I
K
N
Y
R
S
R
A
T
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4L0
874
97729
Y570
L
V
D
S
I
K
N
Y
R
T
R
T
T
I
F
Rat
Rattus norvegicus
XP_001079855
874
97768
Y570
L
V
D
S
I
K
N
Y
R
T
R
T
T
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088266
846
94831
Y547
F
V
D
G
I
K
S
Y
K
S
K
A
T
I
F
Zebra Danio
Brachydanio rerio
NP_775375
862
97037
Y547
M
V
D
T
I
K
G
Y
K
A
K
S
T
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_612028
827
93352
F524
I
L
V
K
M
R
S
F
R
P
G
G
T
V
F
Honey Bee
Apis mellifera
XP_397101
743
84721
Y502
L
L
S
K
I
V
N
Y
R
P
Q
G
T
I
F
Nematode Worm
Caenorhab. elegans
NP_741348
825
93065
M514
K
S
Q
A
L
A
V
M
Q
A
K
R
K
A
H
Sea Urchin
Strong. purpuratus
XP_792708
889
98517
Y545
L
V
D
E
V
K
G
Y
K
P
R
A
T
I
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49289
845
93485
F512
F
F
Q
K
I
K
N
F
R
P
K
Q
T
I
L
Baker's Yeast
Sacchar. cerevisiae
Q12389
995
113139
R682
F
L
A
K
L
Q
N
R
R
N
K
E
T
V
F
Red Bread Mold
Neurospora crassa
Q7S9J4
934
103635
F605
L
L
S
R
I
N
R
F
K
P
Q
E
T
I
F
Conservation
Percent
Protein Identity:
100
98.9
96.8
86.8
N.A.
85.2
85.1
N.A.
N.A.
N.A.
63.3
60.7
N.A.
38.3
43.4
40.6
51.9
Protein Similarity:
100
99.3
97.8
91.5
N.A.
90.9
90.6
N.A.
N.A.
N.A.
76.6
74.6
N.A.
56.5
59.7
58.4
68.7
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
N.A.
66.6
53.3
N.A.
20
53.3
0
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
86.6
93.3
N.A.
66.6
66.6
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
33.8
36
Protein Similarity:
N.A.
N.A.
N.A.
58
50.1
55
P-Site Identity:
N.A.
N.A.
N.A.
40
26.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
66.6
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
7
0
0
0
14
0
40
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
7
0
0
0
0
0
0
0
14
0
0
0
% E
% Phe:
20
7
0
0
0
0
0
20
0
0
0
0
0
0
87
% F
% Gly:
0
0
0
7
0
0
14
0
0
0
7
14
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
0
74
0
0
0
0
0
0
0
0
80
0
% I
% Lys:
7
0
0
27
0
67
0
0
27
0
34
0
7
0
0
% K
% Leu:
60
27
0
0
14
0
0
0
0
0
0
0
0
0
7
% L
% Met:
7
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
60
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% P
% Gln:
0
0
14
0
0
7
0
0
7
0
14
7
0
0
0
% Q
% Arg:
0
0
0
7
0
7
7
7
67
0
47
7
0
0
0
% R
% Ser:
0
7
14
40
0
0
14
0
0
34
0
7
0
0
0
% S
% Thr:
0
0
0
7
0
0
0
0
0
14
0
14
94
0
0
% T
% Val:
0
60
7
0
7
7
7
0
0
0
0
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _