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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCOLN3
All Species:
36.06
Human Site:
T519
Identified Species:
88.15
UniProt:
Q8TDD5
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDD5
NP_060768.8
553
64248
T519
Q
Q
D
G
F
P
E
T
E
L
R
T
F
I
S
Chimpanzee
Pan troglodytes
XP_001140802
553
64157
T519
Q
Q
D
G
F
P
E
T
E
L
R
T
F
I
S
Rhesus Macaque
Macaca mulatta
XP_001108412
553
64361
T519
Q
Q
D
G
F
P
E
T
E
L
R
T
F
I
S
Dog
Lupus familis
XP_547306
808
91395
T774
Q
Q
D
G
F
P
E
T
E
L
R
T
F
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4F0
553
63730
T519
Q
Q
D
G
F
P
E
T
E
L
R
K
F
I
A
Rat
Rattus norvegicus
NP_001012059
553
63894
T519
Q
Q
D
G
F
P
E
T
E
L
R
K
F
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510269
539
62588
T497
Q
Q
N
G
F
P
S
T
D
L
Q
E
F
L
K
Chicken
Gallus gallus
XP_426647
591
68155
T552
Q
Q
D
G
F
P
E
T
E
L
Q
R
F
I
S
Frog
Xenopus laevis
NP_001085683
552
63998
S517
Q
I
G
G
F
P
E
S
E
L
H
T
F
V
S
Zebra Danio
Brachydanio rerio
XP_001336199
565
63585
S532
T
Q
D
V
P
Q
V
S
E
L
H
R
F
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.8
64.3
N.A.
91.1
91.6
N.A.
57.8
76.4
72.8
53.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99
66.2
N.A.
96
96.3
N.A.
75.5
84.9
86.6
73.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
53.3
86.6
66.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
93.3
80
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
80
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
80
0
90
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
90
0
0
0
0
0
0
0
100
0
0
% F
% Gly:
0
0
10
90
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
80
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
10
% K
% Leu:
0
0
0
0
0
0
0
0
0
100
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
90
0
0
0
0
0
0
0
0
0
% P
% Gln:
90
90
0
0
0
10
0
0
0
0
20
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
60
20
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
20
0
0
0
0
0
0
60
% S
% Thr:
10
0
0
0
0
0
0
80
0
0
0
50
0
0
0
% T
% Val:
0
0
0
10
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _