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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRP4
All Species:
16.36
Human Site:
S650
Identified Species:
51.43
UniProt:
Q8TDF6
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDF6
NP_001139674.1
673
74882
S650
Q
T
E
S
P
H
P
S
W
E
T
D
T
V
P
Chimpanzee
Pan troglodytes
XP_524253
673
74822
S650
Q
T
E
S
P
H
P
S
W
E
T
D
T
V
P
Rhesus Macaque
Macaca mulatta
XP_001114059
686
76084
Q650
L
S
L
T
P
L
P
Q
S
V
L
T
P
V
I
Dog
Lupus familis
XP_541642
683
75833
S660
Q
T
E
P
P
N
P
S
W
E
P
E
T
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTM9
673
74889
S650
Q
T
E
S
S
H
S
S
W
E
P
E
V
V
P
Rat
Rattus norvegicus
Q8R5I4
678
75387
S655
Q
T
E
S
S
H
S
S
W
E
P
E
M
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NTL4
791
90153
C681
E
N
E
T
Q
S
L
C
L
Q
V
P
S
P
P
Zebra Danio
Brachydanio rerio
NP_001038327
687
77866
S652
D
A
E
A
A
T
L
S
D
R
S
T
Q
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
88.7
88.8
N.A.
85.7
82.4
N.A.
N.A.
N.A.
41.2
46
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
91.1
92
N.A.
90.1
87.4
N.A.
N.A.
N.A.
56.3
62.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
73.3
N.A.
66.6
66.6
N.A.
N.A.
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
86.6
N.A.
73.3
73.3
N.A.
N.A.
N.A.
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
13
13
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
0
0
0
13
0
0
25
0
0
0
% D
% Glu:
13
0
88
0
0
0
0
0
0
63
0
38
0
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
13
0
13
0
0
13
25
0
13
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
13
0
0
0
13
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
13
50
0
50
0
0
0
38
13
13
13
75
% P
% Gln:
63
0
0
0
13
0
0
13
0
13
0
0
13
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% R
% Ser:
0
13
0
50
25
13
25
75
13
0
13
0
13
0
0
% S
% Thr:
0
63
0
25
0
13
0
0
0
0
25
25
38
13
0
% T
% Val:
0
0
0
0
0
0
0
0
0
13
13
0
13
75
0
% V
% Trp:
0
0
0
0
0
0
0
0
63
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _