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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD5 All Species: 9.09
Human Site: S1391 Identified Species: 16.67
UniProt: Q8TDI0 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDI0 NP_056372.1 1954 223050 S1391 E E R P E G Q S G R R Q S R R
Chimpanzee Pan troglodytes XP_525165 1991 226479 S1391 E E R P E G Q S G R R Q S R R
Rhesus Macaque Macaca mulatta XP_001107319 1912 217912 R1406 P L P P L L A R V G G N I E V
Dog Lupus familis XP_546747 1994 226702 S1436 E E R P E G Q S G R R Q S R R
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 R1399 P L P P L L A R V G G N I E V
Rat Rattus norvegicus Q9JIX5 2581 290674 C1574 K K H L K H Q C N K V L L R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 E1881 N S P P E D K E E S I E I H P
Frog Xenopus laevis NP_001080504 1893 214670 R1397 P L P P L L A R V G G N I E V
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 L1534 R V I L V F C L I H Y R G D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 A1400 R P L P P L L A R V G G N I E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 E1292 E E R R R R R E E R S E K L P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 E936 R K G R D N L E P T P L M E G
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 K1020 S E V R A L Y K A I L K F G N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 70.5 94 N.A. 70.9 23.4 N.A. N.A. 22.8 68.9 23 N.A. 55.4 N.A. 43.3 N.A.
Protein Similarity: 100 95.7 80.5 95.8 N.A. 81.1 38.2 N.A. N.A. 36.4 79.4 38.3 N.A. 69.1 N.A. 58.5 N.A.
P-Site Identity: 100 100 6.6 100 N.A. 6.6 13.3 N.A. N.A. 13.3 6.6 0 N.A. 6.6 N.A. 26.6 N.A.
P-Site Similarity: 100 100 6.6 100 N.A. 6.6 40 N.A. N.A. 26.6 6.6 6.6 N.A. 20 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 25 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 24 8 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 0 0 0 0 0 0 0 8 0 % D
% Glu: 31 39 0 0 31 0 0 24 16 0 0 16 0 31 16 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 0 8 0 0 24 0 0 24 24 31 8 8 8 8 % G
% His: 0 0 8 0 0 8 0 0 0 8 0 0 0 8 0 % H
% Ile: 0 0 8 0 0 0 0 0 8 8 8 0 31 8 0 % I
% Lys: 8 16 0 0 8 0 8 8 0 8 0 8 8 0 0 % K
% Leu: 0 24 8 16 24 39 16 8 0 0 8 16 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 0 0 0 8 0 0 8 0 0 24 8 0 8 % N
% Pro: 24 8 31 62 8 0 0 0 8 0 8 0 0 0 16 % P
% Gln: 0 0 0 0 0 0 31 0 0 0 0 24 0 0 0 % Q
% Arg: 24 0 31 24 8 8 8 24 8 31 24 8 0 31 24 % R
% Ser: 8 8 0 0 0 0 0 24 0 8 8 0 24 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % T
% Val: 0 8 8 0 8 0 0 0 24 8 8 0 0 0 31 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _