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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD5 All Species: 1.21
Human Site: S1539 Identified Species: 2.22
UniProt: Q8TDI0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDI0 NP_056372.1 1954 223050 S1539 E G P E G K K S G E V I S S D
Chimpanzee Pan troglodytes XP_525165 1991 226479 P1539 E G P E G K K P G E V I S S D
Rhesus Macaque Macaca mulatta XP_001107319 1912 217912 M1530 E V E E N K K M S Q P G S P S
Dog Lupus familis XP_546747 1994 226702 P1584 E G P E G K K P S E V I S S D
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 M1523 E V E E N K K M S Q P G S P S
Rat Rattus norvegicus Q9JIX5 2581 290674 L1958 Q D P D F S F L A A R M N Y M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 D2097 W W E C G K H D K D L L I G A
Frog Xenopus laevis NP_001080504 1893 214670 A1521 E A E E N K M A S K I D S P S
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 C1704 C L C F V E R C G R P N E Q D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 S1526 K P C E P V R S A L K Q D V A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 Q1429 K M L A T A A Q A S V S N L P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 P1050 V E D H P G K P V F P S R I L
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 L1134 S L N A E S L L S R V E D L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 70.5 94 N.A. 70.9 23.4 N.A. N.A. 22.8 68.9 23 N.A. 55.4 N.A. 43.3 N.A.
Protein Similarity: 100 95.7 80.5 95.8 N.A. 81.1 38.2 N.A. N.A. 36.4 79.4 38.3 N.A. 69.1 N.A. 58.5 N.A.
P-Site Identity: 100 93.3 33.3 86.6 N.A. 33.3 6.6 N.A. N.A. 13.3 26.6 13.3 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 40 86.6 N.A. 40 33.3 N.A. N.A. 33.3 46.6 26.6 N.A. 26.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 25 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 16 0 8 8 8 24 8 0 0 0 0 16 % A
% Cys: 8 0 16 8 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 8 0 0 0 8 0 8 0 8 16 0 31 % D
% Glu: 47 8 31 54 8 8 0 0 0 24 0 8 8 0 0 % E
% Phe: 0 0 0 8 8 0 8 0 0 8 0 0 0 0 0 % F
% Gly: 0 24 0 0 31 8 0 0 24 0 0 16 0 8 0 % G
% His: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 24 8 8 0 % I
% Lys: 16 0 0 0 0 54 47 0 8 8 8 0 0 0 8 % K
% Leu: 0 16 8 0 0 0 8 16 0 8 8 8 0 16 8 % L
% Met: 0 8 0 0 0 0 8 16 0 0 0 8 0 0 8 % M
% Asn: 0 0 8 0 24 0 0 0 0 0 0 8 16 0 0 % N
% Pro: 0 8 31 0 16 0 0 24 0 0 31 0 0 24 8 % P
% Gln: 8 0 0 0 0 0 0 8 0 16 0 8 0 8 0 % Q
% Arg: 0 0 0 0 0 0 16 0 0 16 8 0 8 0 0 % R
% Ser: 8 0 0 0 0 16 0 16 39 8 0 16 47 24 24 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % T
% Val: 8 16 0 0 8 8 0 0 8 0 39 0 0 8 0 % V
% Trp: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _