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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD5 All Species: 13.64
Human Site: S305 Identified Species: 25
UniProt: Q8TDI0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDI0 NP_056372.1 1954 223050 S305 E S D F D S A S I H S A S V R
Chimpanzee Pan troglodytes XP_525165 1991 226479 S307 S P P Q V A A S L T S P Q P C
Rhesus Macaque Macaca mulatta XP_001107319 1912 217912 S332 S I N S Y S V S D G S T S R S
Dog Lupus familis XP_546747 1994 226702 S350 E S D L D S A S I H S S S V R
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 S325 S I N S Y S V S D G S T S R S
Rat Rattus norvegicus Q9JIX5 2581 290674 T288 Q G E S K R I T L V L Q Q P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 P396 P Q G T Y A S P P P M S P M K
Frog Xenopus laevis NP_001080504 1893 214670 S315 D S D Y D E G S M N S L S V S
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 A428 K V I N T S A A G S T S G T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 A339 A Q D D G S G A P V V R K K A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 H264 Q G V V E E N H Q E N C E V C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 D77 E D S G E D E D E E D F E E D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 70.5 94 N.A. 70.9 23.4 N.A. N.A. 22.8 68.9 23 N.A. 55.4 N.A. 43.3 N.A.
Protein Similarity: 100 95.7 80.5 95.8 N.A. 81.1 38.2 N.A. N.A. 36.4 79.4 38.3 N.A. 69.1 N.A. 58.5 N.A.
P-Site Identity: 100 20 26.6 86.6 N.A. 26.6 0 N.A. N.A. 0 46.6 13.3 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 33.3 33.3 93.3 N.A. 33.3 33.3 N.A. N.A. 33.3 73.3 40 N.A. 20 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 25 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 16 31 16 0 0 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 16 % C
% Asp: 8 8 31 8 24 8 0 8 16 0 8 0 0 0 8 % D
% Glu: 24 0 8 0 16 16 8 0 8 16 0 0 16 8 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 16 8 8 8 0 16 0 8 16 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 16 0 0 0 0 0 % H
% Ile: 0 16 8 0 0 0 8 0 16 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 8 0 0 0 0 0 0 0 8 8 8 % K
% Leu: 0 0 0 8 0 0 0 0 16 0 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 8 0 0 8 0 % M
% Asn: 0 0 16 8 0 0 8 0 0 8 8 0 0 0 0 % N
% Pro: 8 8 8 0 0 0 0 8 16 8 0 8 8 16 0 % P
% Gln: 16 16 0 8 0 0 0 0 8 0 0 8 16 0 8 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 8 0 16 16 % R
% Ser: 24 24 8 24 0 47 8 47 0 8 47 24 39 0 24 % S
% Thr: 0 0 0 8 8 0 0 8 0 8 8 16 0 8 8 % T
% Val: 0 8 8 8 8 0 16 0 0 16 8 0 0 31 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 24 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _