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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD5 All Species: 5.15
Human Site: S323 Identified Species: 9.44
UniProt: Q8TDI0 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.42
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDI0 NP_056372.1 1954 223050 S323 S A A L G K K S K R R R K K K
Chimpanzee Pan troglodytes XP_525165 1991 226479 H325 E L E A L S L H H G R S Q F D
Rhesus Macaque Macaca mulatta XP_001107319 1912 217912 K350 R K K L R T T K K K K K G E E
Dog Lupus familis XP_546747 1994 226702 S368 S T A L G K K S K R R R K K K
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 K343 R K K L R T A K K K K K G E E
Rat Rattus norvegicus Q9JIX5 2581 290674 V306 P Q G H R H V V L G S L P G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 P414 N P A G T P P P Q V R P G S A
Frog Xenopus laevis NP_001080504 1893 214670 R333 T S K S S R S R K K L K A T K
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 A446 A S S G V R L A K I Q E P V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 K357 I G N K F K K K N K L K K T K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 T282 G E L M L C D T C T R A Y H V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 R11 L V E R L R I R S D R K P V Y
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 N95 Y G S P I K Q N R S K P K S R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 70.5 94 N.A. 70.9 23.4 N.A. N.A. 22.8 68.9 23 N.A. 55.4 N.A. 43.3 N.A.
Protein Similarity: 100 95.7 80.5 95.8 N.A. 81.1 38.2 N.A. N.A. 36.4 79.4 38.3 N.A. 69.1 N.A. 58.5 N.A.
P-Site Identity: 100 6.6 13.3 93.3 N.A. 13.3 6.6 N.A. N.A. 13.3 13.3 6.6 N.A. 26.6 N.A. 6.6 N.A.
P-Site Similarity: 100 13.3 46.6 93.3 N.A. 46.6 6.6 N.A. N.A. 26.6 46.6 53.3 N.A. 40 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 25 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 24 8 0 0 8 8 0 0 0 8 8 0 8 % A
% Cys: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 8 % D
% Glu: 8 8 16 0 0 0 0 0 0 0 0 8 0 16 16 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 8 16 8 16 16 0 0 0 0 16 0 0 24 8 0 % G
% His: 0 0 0 8 0 8 0 8 8 0 0 0 0 8 0 % H
% Ile: 8 0 0 0 8 0 8 0 0 8 0 0 0 0 0 % I
% Lys: 0 16 24 8 0 31 24 24 47 31 24 39 31 16 39 % K
% Leu: 8 8 8 31 24 0 16 0 8 0 16 8 0 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 0 0 0 0 8 8 0 0 0 0 0 0 % N
% Pro: 8 8 0 8 0 8 8 8 0 0 0 16 24 0 0 % P
% Gln: 0 8 0 0 0 0 8 0 8 0 8 0 8 0 0 % Q
% Arg: 16 0 0 8 24 24 0 16 8 16 47 16 0 0 16 % R
% Ser: 16 16 16 8 8 8 8 16 8 8 8 8 0 16 0 % S
% Thr: 8 8 0 0 8 16 8 8 0 8 0 0 0 16 0 % T
% Val: 0 8 0 0 8 0 8 8 0 8 0 0 0 16 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _