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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD5
All Species:
5.45
Human Site:
S496
Identified Species:
10
UniProt:
Q8TDI0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDI0
NP_056372.1
1954
223050
S496
P
G
P
D
V
E
P
S
L
P
P
P
K
P
L
Chimpanzee
Pan troglodytes
XP_525165
1991
226479
S496
P
G
P
D
V
E
P
S
L
P
P
P
K
P
L
Rhesus Macaque
Macaca mulatta
XP_001107319
1912
217912
N528
R
P
P
D
A
D
P
N
T
P
S
P
K
P
L
Dog
Lupus familis
XP_546747
1994
226702
G541
P
G
P
D
V
E
P
G
V
P
P
P
K
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDQ2
1915
217732
N521
R
P
P
D
A
D
P
N
T
P
S
P
K
P
L
Rat
Rattus norvegicus
Q9JIX5
2581
290674
E488
P
R
V
L
N
E
D
E
L
P
S
V
R
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q06A37
3011
338194
P571
S
E
P
F
L
E
K
P
V
P
D
M
T
Q
V
Frog
Xenopus laevis
NP_001080504
1893
214670
D518
R
P
A
D
S
D
P
D
A
A
P
L
K
P
L
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
P591
S
D
V
D
L
S
P
P
V
S
P
R
T
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
S516
T
S
K
G
S
K
N
S
N
S
R
V
R
E
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
F412
E
A
S
K
D
D
V
F
L
K
P
P
R
K
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
Q130
P
K
P
I
F
V
K
Q
Y
L
V
K
W
K
G
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
L214
C
K
E
N
Y
E
F
L
I
K
W
T
D
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
70.5
94
N.A.
70.9
23.4
N.A.
N.A.
22.8
68.9
23
N.A.
55.4
N.A.
43.3
N.A.
Protein Similarity:
100
95.7
80.5
95.8
N.A.
81.1
38.2
N.A.
N.A.
36.4
79.4
38.3
N.A.
69.1
N.A.
58.5
N.A.
P-Site Identity:
100
100
53.3
86.6
N.A.
53.3
33.3
N.A.
N.A.
20
40
20
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
66.6
93.3
N.A.
66.6
40
N.A.
N.A.
40
46.6
33.3
N.A.
20
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
16
0
0
0
8
8
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
54
8
31
8
8
0
0
8
0
8
0
0
% D
% Glu:
8
8
8
0
0
47
0
8
0
0
0
0
0
16
16
% E
% Phe:
0
0
0
8
8
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
24
0
8
0
0
0
8
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
16
8
8
0
8
16
0
0
16
0
8
47
16
0
% K
% Leu:
0
0
0
8
16
0
0
8
31
8
0
8
0
8
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
0
8
8
0
8
16
8
0
0
0
0
0
0
% N
% Pro:
39
24
54
0
0
0
54
16
0
54
47
47
0
54
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
24
8
0
0
0
0
0
0
0
0
8
8
24
0
0
% R
% Ser:
16
8
8
0
16
8
0
24
0
16
24
0
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
16
0
0
8
16
0
0
% T
% Val:
0
0
16
0
24
8
8
0
24
0
8
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _