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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD5 All Species: 35.45
Human Site: T1169 Identified Species: 65
UniProt: Q8TDI0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDI0 NP_056372.1 1954 223050 T1169 A K R K M M L T H L V V R P G
Chimpanzee Pan troglodytes XP_525165 1991 226479 T1169 A K R K M M L T H L V V R P G
Rhesus Macaque Macaca mulatta XP_001107319 1912 217912 T1195 A K K K M M L T H L V V R P G
Dog Lupus familis XP_546747 1994 226702 T1214 A K R K M M L T H L V V R P G
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 T1188 A K K K M M L T H L V V R P G
Rat Rattus norvegicus Q9JIX5 2581 290674 D1278 A S L K L G L D K A V L Q S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 D1436 A S L K L G L D K A V L Q S M
Frog Xenopus laevis NP_001080504 1893 214670 T1186 A K K K M M L T H L V V R P G
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 D1315 A S L K L G L D R A V L Q S M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 T1197 A K R K M M L T H L V V R P G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 T1085 A K K K M L L T H L V V R A G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 T733 E E R M M Q L T K K K M V L E
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 Y817 Q K N H V M V Y R L V S K D T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 70.5 94 N.A. 70.9 23.4 N.A. N.A. 22.8 68.9 23 N.A. 55.4 N.A. 43.3 N.A.
Protein Similarity: 100 95.7 80.5 95.8 N.A. 81.1 38.2 N.A. N.A. 36.4 79.4 38.3 N.A. 69.1 N.A. 58.5 N.A.
P-Site Identity: 100 100 93.3 100 N.A. 93.3 26.6 N.A. N.A. 26.6 93.3 26.6 N.A. 100 N.A. 80 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 46.6 N.A. N.A. 46.6 100 46.6 N.A. 100 N.A. 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 25 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 85 0 0 0 0 0 0 0 0 24 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 24 0 0 0 0 0 8 0 % D
% Glu: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 24 0 0 0 0 0 0 0 0 62 % G
% His: 0 0 0 8 0 0 0 0 62 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 70 31 85 0 0 0 0 24 8 8 0 8 0 0 % K
% Leu: 0 0 24 0 24 8 93 0 0 70 0 24 0 8 0 % L
% Met: 0 0 0 8 70 62 0 0 0 0 0 8 0 0 24 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 54 0 % P
% Gln: 8 0 0 0 0 8 0 0 0 0 0 0 24 0 0 % Q
% Arg: 0 0 39 0 0 0 0 0 16 0 0 0 62 0 0 % R
% Ser: 0 24 0 0 0 0 0 0 0 0 0 8 0 24 0 % S
% Thr: 0 0 0 0 0 0 0 70 0 0 0 0 0 0 8 % T
% Val: 0 0 0 0 8 0 8 0 0 0 93 62 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _