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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD5
All Species:
22.73
Human Site:
T677
Identified Species:
41.67
UniProt:
Q8TDI0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDI0
NP_056372.1
1954
223050
T677
K
Q
E
K
P
P
D
T
P
I
V
D
P
T
V
Chimpanzee
Pan troglodytes
XP_525165
1991
226479
T677
K
Q
E
K
P
P
D
T
P
I
V
D
P
T
V
Rhesus Macaque
Macaca mulatta
XP_001107319
1912
217912
T703
K
L
E
R
P
P
E
T
P
T
V
D
P
T
V
Dog
Lupus familis
XP_546747
1994
226702
T722
K
Q
E
K
P
P
D
T
P
I
V
D
P
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDQ2
1915
217732
T696
K
L
E
R
P
P
E
T
P
T
V
D
P
T
V
Rat
Rattus norvegicus
Q9JIX5
2581
290674
N720
H
E
D
E
E
P
F
N
P
D
Y
V
E
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q06A37
3011
338194
L921
Y
E
D
S
T
W
E
L
K
Q
D
I
D
Q
A
Frog
Xenopus laevis
NP_001080504
1893
214670
T694
K
L
D
R
P
P
D
T
P
A
V
D
P
T
V
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
T824
R
Q
P
R
L
K
R
T
P
R
P
A
A
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
K707
H
Y
T
P
P
P
E
K
P
T
T
D
L
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
R593
V
T
S
R
R
K
K
R
E
K
I
D
I
L
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
H293
F
S
W
S
K
Q
T
H
V
I
L
A
D
E
M
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
R377
F
I
K
G
G
E
L
R
D
F
Q
L
T
G
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
70.5
94
N.A.
70.9
23.4
N.A.
N.A.
22.8
68.9
23
N.A.
55.4
N.A.
43.3
N.A.
Protein Similarity:
100
95.7
80.5
95.8
N.A.
81.1
38.2
N.A.
N.A.
36.4
79.4
38.3
N.A.
69.1
N.A.
58.5
N.A.
P-Site Identity:
100
100
73.3
100
N.A.
73.3
13.3
N.A.
N.A.
0
73.3
20
N.A.
26.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
86.6
33.3
N.A.
N.A.
20
86.6
40
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.2
41.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
16
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
24
0
0
0
31
0
8
8
8
62
16
0
8
% D
% Glu:
0
16
39
8
8
8
31
0
8
0
0
0
8
8
0
% E
% Phe:
16
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% G
% His:
16
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
31
8
8
8
0
8
% I
% Lys:
47
0
8
24
8
16
8
8
8
8
0
0
0
8
16
% K
% Leu:
0
24
0
0
8
0
8
8
0
0
8
8
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
8
54
62
0
0
70
0
8
0
47
0
0
% P
% Gln:
0
31
0
0
0
8
0
0
0
8
8
0
0
8
0
% Q
% Arg:
8
0
0
39
8
0
8
16
0
8
0
0
0
0
0
% R
% Ser:
0
8
8
16
0
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
8
8
0
8
0
8
54
0
24
8
0
8
47
0
% T
% Val:
8
0
0
0
0
0
0
0
8
0
47
8
0
8
47
% V
% Trp:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _