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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD5 All Species: 9.09
Human Site: Y1293 Identified Species: 16.67
UniProt: Q8TDI0 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDI0 NP_056372.1 1954 223050 Y1293 S S F K V A Q Y V V R E E D G
Chimpanzee Pan troglodytes XP_525165 1991 226479 Y1293 S S F K V A Q Y V V R E E D G
Rhesus Macaque Macaca mulatta XP_001107319 1912 217912 R1319 D Y W E K L L R H H Y E Q Q Q
Dog Lupus familis XP_546747 1994 226702 Y1338 S S F K V A Q Y V V R E E D G
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 R1312 D Y W E K L L R H H Y E Q Q Q
Rat Rattus norvegicus Q9JIX5 2581 290674 R1402 V I D T P R V R K Q T R H F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 R1560 V I D T P R V R K Q T R L Y S
Frog Xenopus laevis NP_001080504 1893 214670 R1310 D Y W E K L L R H H Y E Q Q Q
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 Q1439 D T P R V R K Q T R Q F S S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 G1321 E D V G R S L G K G K R V R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 Q1209 I K E G T E E Q D P N Y W E K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 E857 D R A S Y W E E L L K D K F E
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 L941 D I I P E E E L K K L Q D E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 70.5 94 N.A. 70.9 23.4 N.A. N.A. 22.8 68.9 23 N.A. 55.4 N.A. 43.3 N.A.
Protein Similarity: 100 95.7 80.5 95.8 N.A. 81.1 38.2 N.A. N.A. 36.4 79.4 38.3 N.A. 69.1 N.A. 58.5 N.A.
P-Site Identity: 100 100 6.6 100 N.A. 6.6 0 N.A. N.A. 0 6.6 6.6 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 26.6 0 N.A. N.A. 0 26.6 33.3 N.A. 13.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 25 N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 41.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 24 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 47 8 16 0 0 0 0 0 8 0 0 8 8 24 0 % D
% Glu: 8 0 8 24 8 16 24 8 0 0 0 47 24 16 16 % E
% Phe: 0 0 24 0 0 0 0 0 0 0 0 8 0 16 0 % F
% Gly: 0 0 0 16 0 0 0 8 0 8 0 0 0 0 24 % G
% His: 0 0 0 0 0 0 0 0 24 24 0 0 8 0 0 % H
% Ile: 8 24 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 24 24 0 8 0 31 8 16 0 8 0 16 % K
% Leu: 0 0 0 0 0 24 31 8 8 8 8 0 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 8 8 16 0 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 24 16 0 16 8 8 24 24 24 % Q
% Arg: 0 8 0 8 8 24 0 39 0 8 24 24 0 8 0 % R
% Ser: 24 24 0 8 0 8 0 0 0 0 0 0 8 8 16 % S
% Thr: 0 8 0 16 8 0 0 0 8 0 16 0 0 0 0 % T
% Val: 16 0 8 0 31 0 16 0 24 24 0 0 8 0 0 % V
% Trp: 0 0 24 0 0 8 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 24 0 0 8 0 0 24 0 0 24 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _