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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMC1
All Species:
0
Human Site:
S128
Identified Species:
0
UniProt:
Q8TDI8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDI8
NP_619636.2
760
87768
S128
K
E
A
K
K
F
V
S
E
N
E
G
A
L
G
Chimpanzee
Pan troglodytes
XP_528322
760
87690
Rhesus Macaque
Macaca mulatta
XP_001093188
807
93201
Dog
Lupus familis
XP_541284
859
98517
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4P5
757
87246
Rat
Rattus norvegicus
Q496Z4
698
78193
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512038
976
111408
Chicken
Gallus gallus
Q5YCC7
1138
128744
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695621
820
93823
Tiger Blowfish
Takifugu rubipres
NP_001041502
956
108121
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11069
1203
136041
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
92.4
85.2
N.A.
95.9
22.6
N.A.
49
28.2
N.A.
55.8
44.1
N.A.
N.A.
21.9
N.A.
Protein Similarity:
100
99.6
92.8
86.3
N.A.
97.6
43
N.A.
62.7
42.7
N.A.
72
57.6
N.A.
N.A.
36.9
N.A.
P-Site Identity:
100
0
0
0
N.A.
0
0
N.A.
0
0
N.A.
0
0
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
0
0
0
N.A.
0
0
N.A.
0
0
N.A.
0
0
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
100
0
0
0
0
0
0
0
0
0
100
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
100
0
0
0
0
0
0
100
0
100
0
0
0
0
% E
% Phe:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
100
0
0
100
100
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _