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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DMXL2 All Species: 13.64
Human Site: S1240 Identified Species: 30
UniProt: Q8TDJ6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDJ6 NP_056078.2 3036 339758 S1240 L R S I D L V S S V D G T P S
Chimpanzee Pan troglodytes XP_510406 3036 339748 S1240 L R S I D L V S S V D G T P S
Rhesus Macaque Macaca mulatta XP_001087241 3025 337728 W1221 P F P V S L S W V R D G I L V
Dog Lupus familis XP_535481 3036 340032 S1239 L R S I D L V S S V D G T P S
Cat Felis silvestris
Mouse Mus musculus Q8BPN8 3032 338190 S1241 L R S I D L V S S V D G T P S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520974 2200 241353 I556 I L W R V D P I G P L S Y T G
Chicken Gallus gallus XP_424958 2833 314679 N1189 A G E V V A I N E S E S N H D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665441 3003 332749 G1204 N L V S S V D G T P S L P V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572302 3419 376907 D1415 L D W V S K E D G S H I L T V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_510431 2948 330673 N1239 Q E K T K S S N P A A N P N I
Sea Urchin Strong. purpuratus XP_790747 3216 355082 V1221 A P V S T E F V E A G A N G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 56 95.5 N.A. 92.9 N.A. N.A. 56.8 51.1 N.A. 70.4 N.A. 37.8 N.A. 31.2 39
Protein Similarity: 100 99.7 71.8 97.8 N.A. 96.4 N.A. N.A. 62.8 66.3 N.A. 81.5 N.A. 55.7 N.A. 50.9 57.3
P-Site Identity: 100 100 20 100 N.A. 100 N.A. N.A. 0 0 N.A. 6.6 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 100 26.6 100 N.A. 100 N.A. N.A. 6.6 26.6 N.A. 20 N.A. 13.3 N.A. 6.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 0 0 10 0 0 0 19 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 37 10 10 10 0 0 46 0 0 0 10 % D
% Glu: 0 10 10 0 0 10 10 0 19 0 10 0 0 0 0 % E
% Phe: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 10 19 0 10 46 0 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % H
% Ile: 10 0 0 37 0 0 10 10 0 0 0 10 10 0 10 % I
% Lys: 0 0 10 0 10 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 46 19 0 0 0 46 0 0 0 0 10 10 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 19 0 0 0 10 19 10 0 % N
% Pro: 10 10 10 0 0 0 10 0 10 19 0 0 19 37 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 37 0 10 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 37 19 28 10 19 37 37 19 10 19 0 0 46 % S
% Thr: 0 0 0 10 10 0 0 0 10 0 0 0 37 19 0 % T
% Val: 0 0 19 28 19 10 37 10 10 37 0 0 0 10 28 % V
% Trp: 0 0 19 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _