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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DMXL2
All Species:
14.55
Human Site:
S2123
Identified Species:
32
UniProt:
Q8TDJ6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDJ6
NP_056078.2
3036
339758
S2123
V
D
K
P
D
I
G
S
Y
E
R
H
Q
I
E
Chimpanzee
Pan troglodytes
XP_510406
3036
339748
S2123
V
D
K
P
D
I
G
S
Y
E
R
H
Q
I
E
Rhesus Macaque
Macaca mulatta
XP_001087241
3025
337728
H2105
E
D
A
E
D
L
P
H
Q
M
K
V
K
Q
L
Dog
Lupus familis
XP_535481
3036
340032
S2121
T
D
K
P
D
I
G
S
Y
E
R
H
Q
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPN8
3032
338190
S2118
V
D
K
P
D
I
G
S
Y
E
R
H
Q
I
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520974
2200
241353
L1383
S
G
P
G
R
D
T
L
D
E
C
G
L
R
Y
Chicken
Gallus gallus
XP_424958
2833
314679
A2016
L
F
A
C
T
A
S
A
K
T
V
V
A
N
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665441
3003
332749
A2091
L
I
R
G
E
A
G
A
Y
E
R
H
Q
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572302
3419
376907
D2451
L
H
E
I
L
M
Q
D
K
Q
D
F
E
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510431
2948
330673
S2099
Y
D
Q
P
S
D
L
S
K
L
S
R
A
S
P
Sea Urchin
Strong. purpuratus
XP_790747
3216
355082
Q2267
G
T
L
Y
E
Q
L
Q
A
K
R
L
D
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
56
95.5
N.A.
92.9
N.A.
N.A.
56.8
51.1
N.A.
70.4
N.A.
37.8
N.A.
31.2
39
Protein Similarity:
100
99.7
71.8
97.8
N.A.
96.4
N.A.
N.A.
62.8
66.3
N.A.
81.5
N.A.
55.7
N.A.
50.9
57.3
P-Site Identity:
100
100
13.3
93.3
N.A.
100
N.A.
N.A.
6.6
0
N.A.
46.6
N.A.
0
N.A.
20
13.3
P-Site Similarity:
100
100
33.3
93.3
N.A.
100
N.A.
N.A.
6.6
13.3
N.A.
80
N.A.
40
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
19
0
19
10
0
0
0
19
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
55
0
0
46
19
0
10
10
0
10
0
10
0
0
% D
% Glu:
10
0
10
10
19
0
0
0
0
55
0
0
10
0
55
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
10
0
19
0
0
46
0
0
0
0
10
0
0
0
% G
% His:
0
10
0
0
0
0
0
10
0
0
0
46
0
0
0
% H
% Ile:
0
10
0
10
0
37
0
0
0
0
0
0
0
37
0
% I
% Lys:
0
0
37
0
0
0
0
0
28
10
10
0
10
0
10
% K
% Leu:
28
0
10
0
10
10
19
10
0
10
0
10
10
10
10
% L
% Met:
0
0
0
0
0
10
0
0
0
10
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
10
46
0
0
10
0
0
0
0
0
0
0
19
% P
% Gln:
0
0
10
0
0
10
10
10
10
10
0
0
46
10
0
% Q
% Arg:
0
0
10
0
10
0
0
0
0
0
55
10
0
10
0
% R
% Ser:
10
0
0
0
10
0
10
46
0
0
10
0
0
10
0
% S
% Thr:
10
10
0
0
10
0
10
0
0
10
0
0
0
0
0
% T
% Val:
28
0
0
0
0
0
0
0
0
0
10
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
0
0
0
46
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _