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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DMXL2
All Species:
27.88
Human Site:
S2197
Identified Species:
61.33
UniProt:
Q8TDJ6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDJ6
NP_056078.2
3036
339758
S2197
T
T
V
K
Q
L
Q
S
P
L
P
L
P
T
T
Chimpanzee
Pan troglodytes
XP_510406
3036
339748
S2197
T
T
V
K
Q
L
Q
S
P
L
P
L
P
T
T
Rhesus Macaque
Macaca mulatta
XP_001087241
3025
337728
S2172
T
S
E
P
L
F
S
S
P
L
S
E
Q
T
S
Dog
Lupus familis
XP_535481
3036
340032
S2195
T
T
V
K
Q
L
Q
S
P
L
P
L
P
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPN8
3032
338190
S2192
T
T
V
K
Q
L
Q
S
P
L
P
L
P
T
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520974
2200
241353
E1450
R
G
D
P
Q
W
S
E
L
R
A
V
G
L
G
Chicken
Gallus gallus
XP_424958
2833
314679
S2083
L
S
D
S
A
V
N
S
A
P
F
S
E
I
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665441
3003
332749
S2165
M
T
V
K
Q
L
Q
S
P
L
P
L
P
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572302
3419
376907
S2518
K
T
Q
Q
Q
L
L
S
P
L
P
F
P
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510431
2948
330673
L2167
D
D
I
V
S
K
Q
L
M
A
T
G
V
N
T
Sea Urchin
Strong. purpuratus
XP_790747
3216
355082
S2336
R
I
V
Q
Q
L
S
S
P
L
P
I
P
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
56
95.5
N.A.
92.9
N.A.
N.A.
56.8
51.1
N.A.
70.4
N.A.
37.8
N.A.
31.2
39
Protein Similarity:
100
99.7
71.8
97.8
N.A.
96.4
N.A.
N.A.
62.8
66.3
N.A.
81.5
N.A.
55.7
N.A.
50.9
57.3
P-Site Identity:
100
100
33.3
100
N.A.
100
N.A.
N.A.
6.6
6.6
N.A.
93.3
N.A.
66.6
N.A.
13.3
66.6
P-Site Similarity:
100
100
46.6
100
N.A.
100
N.A.
N.A.
13.3
20
N.A.
93.3
N.A.
73.3
N.A.
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
10
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
19
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
10
0
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
10
10
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
10
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
10
0
10
0
% I
% Lys:
10
0
0
46
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
10
64
10
10
10
73
0
46
0
10
0
% L
% Met:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
10
% N
% Pro:
0
0
0
19
0
0
0
0
73
10
64
0
64
0
0
% P
% Gln:
0
0
10
19
73
0
55
0
0
0
0
0
10
0
0
% Q
% Arg:
19
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
19
0
10
10
0
28
82
0
0
10
10
0
0
10
% S
% Thr:
46
55
0
0
0
0
0
0
0
0
10
0
0
73
73
% T
% Val:
0
0
55
10
0
10
0
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _