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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DMXL2 All Species: 14.55
Human Site: S2741 Identified Species: 32
UniProt: Q8TDJ6 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDJ6 NP_056078.2 3036 339758 S2741 A S Q V H P P S S L P W L G T
Chimpanzee Pan troglodytes XP_510406 3036 339748 S2741 A S Q V H P P S S L P W L G T
Rhesus Macaque Macaca mulatta XP_001087241 3025 337728 P2719 T H S N P G T P I N M P W L G
Dog Lupus familis XP_535481 3036 340032 S2741 A S Q V H P P S S L P W L G S
Cat Felis silvestris
Mouse Mus musculus Q8BPN8 3032 338190 P2737 S S Q P H P P P S L P W L G S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520974 2200 241353 R1929 E R H Q V E R R R L Q A K R E
Chicken Gallus gallus XP_424958 2833 314679 L2562 R M A S H P T L P Y Y L T G A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665441 3003 332749 S2708 P Q Q M A A S S S M P W L G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572302 3419 376907 S3126 N S N A Y S E S N A S T Q S A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_510431 2948 330673 Y2646 A L R D N D D Y Q I F T D T N
Sea Urchin Strong. purpuratus XP_790747 3216 355082 M2912 Q M E D E F F M V E P K S I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 56 95.5 N.A. 92.9 N.A. N.A. 56.8 51.1 N.A. 70.4 N.A. 37.8 N.A. 31.2 39
Protein Similarity: 100 99.7 71.8 97.8 N.A. 96.4 N.A. N.A. 62.8 66.3 N.A. 81.5 N.A. 55.7 N.A. 50.9 57.3
P-Site Identity: 100 100 0 93.3 N.A. 73.3 N.A. N.A. 6.6 20 N.A. 53.3 N.A. 13.3 N.A. 6.6 6.6
P-Site Similarity: 100 100 0 100 N.A. 86.6 N.A. N.A. 6.6 20 N.A. 66.6 N.A. 26.6 N.A. 26.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 37 0 10 10 10 10 0 0 0 10 0 10 0 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 19 0 10 10 0 0 0 0 0 10 0 0 % D
% Glu: 10 0 10 0 10 10 10 0 0 10 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 10 10 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 0 55 10 % G
% His: 0 10 10 0 46 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 10 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % K
% Leu: 0 10 0 0 0 0 0 10 0 46 0 10 46 10 0 % L
% Met: 0 19 0 10 0 0 0 10 0 10 10 0 0 0 0 % M
% Asn: 10 0 10 10 10 0 0 0 10 10 0 0 0 0 10 % N
% Pro: 10 0 0 10 10 46 37 19 10 0 55 10 0 0 10 % P
% Gln: 10 10 46 10 0 0 0 0 10 0 10 0 10 0 0 % Q
% Arg: 10 10 10 0 0 0 10 10 10 0 0 0 0 10 0 % R
% Ser: 10 46 10 10 0 10 10 46 46 0 10 0 10 10 19 % S
% Thr: 10 0 0 0 0 0 19 0 0 0 0 19 10 10 28 % T
% Val: 0 0 0 28 10 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 46 10 0 0 % W
% Tyr: 0 0 0 0 10 0 0 10 0 10 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _