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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DMXL2
All Species:
14.55
Human Site:
S289
Identified Species:
32
UniProt:
Q8TDJ6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDJ6
NP_056078.2
3036
339758
S289
Q
I
C
E
T
T
T
S
S
I
A
S
S
L
S
Chimpanzee
Pan troglodytes
XP_510406
3036
339748
S289
Q
I
C
E
T
T
T
S
S
I
A
S
S
L
S
Rhesus Macaque
Macaca mulatta
XP_001087241
3025
337728
G288
G
D
Y
S
H
W
T
G
S
I
N
L
T
N
N
Dog
Lupus familis
XP_535481
3036
340032
S289
Q
I
C
E
T
T
T
S
S
V
A
S
N
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPN8
3032
338190
S289
Q
I
C
E
T
T
T
S
S
V
A
S
N
L
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520974
2200
241353
Chicken
Gallus gallus
XP_424958
2833
314679
N259
P
F
V
V
H
W
L
N
N
K
E
L
H
F
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665441
3003
332749
F269
I
S
E
N
S
T
S
F
S
S
S
L
P
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572302
3419
376907
S312
T
Q
F
D
P
M
A
S
Q
N
P
K
F
R
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510431
2948
330673
E294
P
I
L
M
S
W
C
E
D
R
T
S
R
I
W
Sea Urchin
Strong. purpuratus
XP_790747
3216
355082
G269
E
L
H
R
Y
Y
H
G
K
V
Q
R
N
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
56
95.5
N.A.
92.9
N.A.
N.A.
56.8
51.1
N.A.
70.4
N.A.
37.8
N.A.
31.2
39
Protein Similarity:
100
99.7
71.8
97.8
N.A.
96.4
N.A.
N.A.
62.8
66.3
N.A.
81.5
N.A.
55.7
N.A.
50.9
57.3
P-Site Identity:
100
100
20
80
N.A.
86.6
N.A.
N.A.
0
0
N.A.
13.3
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
100
33.3
100
N.A.
100
N.A.
N.A.
0
20
N.A.
33.3
N.A.
20
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
37
0
0
0
0
% A
% Cys:
0
0
37
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
10
37
0
0
0
10
0
0
10
0
0
0
0
% E
% Phe:
0
10
10
0
0
0
0
10
0
0
0
0
10
10
0
% F
% Gly:
10
0
0
0
0
0
0
19
0
0
0
0
0
10
0
% G
% His:
0
0
10
0
19
0
10
0
0
0
0
0
10
0
0
% H
% Ile:
10
46
0
0
0
0
0
0
0
28
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% K
% Leu:
0
10
10
0
0
0
10
0
0
0
0
28
0
37
10
% L
% Met:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
10
0
0
0
10
10
10
10
0
28
19
10
% N
% Pro:
19
0
0
0
10
0
0
0
0
0
10
0
10
0
0
% P
% Gln:
37
10
0
0
0
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
10
0
10
10
10
0
% R
% Ser:
0
10
0
10
19
0
10
46
55
10
10
46
19
0
28
% S
% Thr:
10
0
0
0
37
46
46
0
0
0
10
0
10
0
28
% T
% Val:
0
0
10
10
0
0
0
0
0
28
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
10
0
10
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _