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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DMXL2
All Species:
12.42
Human Site:
S953
Identified Species:
27.33
UniProt:
Q8TDJ6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDJ6
NP_056078.2
3036
339758
S953
P
E
T
S
P
S
V
S
P
M
P
H
S
S
S
Chimpanzee
Pan troglodytes
XP_510406
3036
339748
S953
P
E
T
S
P
S
V
S
P
M
P
H
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001087241
3025
337728
T940
C
R
A
N
L
Q
S
T
S
K
L
T
L
F
S
Dog
Lupus familis
XP_535481
3036
340032
S953
P
E
T
S
P
S
V
S
P
M
P
H
S
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPN8
3032
338190
S952
S
S
P
E
T
S
S
S
M
S
S
V
P
H
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520974
2200
241353
D275
R
G
L
R
M
K
L
D
H
E
L
S
M
D
R
Chicken
Gallus gallus
XP_424958
2833
314679
I908
D
F
V
M
H
V
S
I
F
E
C
E
S
T
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665441
3003
332749
P918
D
I
T
P
G
H
S
P
L
P
R
S
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572302
3419
376907
Q1093
I
V
I
S
S
K
Q
Q
S
S
F
L
S
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510431
2948
330673
S954
A
K
A
T
D
P
V
S
P
N
K
F
E
W
R
Sea Urchin
Strong. purpuratus
XP_790747
3216
355082
A918
S
D
F
S
D
G
D
A
S
N
Q
Y
D
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
56
95.5
N.A.
92.9
N.A.
N.A.
56.8
51.1
N.A.
70.4
N.A.
37.8
N.A.
31.2
39
Protein Similarity:
100
99.7
71.8
97.8
N.A.
96.4
N.A.
N.A.
62.8
66.3
N.A.
81.5
N.A.
55.7
N.A.
50.9
57.3
P-Site Identity:
100
100
6.6
93.3
N.A.
20
N.A.
N.A.
0
6.6
N.A.
26.6
N.A.
13.3
N.A.
20
13.3
P-Site Similarity:
100
100
20
100
N.A.
20
N.A.
N.A.
6.6
13.3
N.A.
26.6
N.A.
20
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
0
0
0
0
10
0
0
0
0
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
19
10
0
0
19
0
10
10
0
0
0
0
10
10
0
% D
% Glu:
0
28
0
10
0
0
0
0
0
19
0
10
10
10
10
% E
% Phe:
0
10
10
0
0
0
0
0
10
0
10
10
0
10
0
% F
% Gly:
0
10
0
0
10
10
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
10
10
0
0
10
0
0
28
0
10
0
% H
% Ile:
10
10
10
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
19
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
0
10
0
10
0
10
0
10
0
19
10
10
0
0
% L
% Met:
0
0
0
10
10
0
0
0
10
28
0
0
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
19
0
0
0
0
0
% N
% Pro:
28
0
10
10
28
10
0
10
37
10
28
0
10
0
0
% P
% Gln:
0
0
0
0
0
10
10
10
0
0
10
0
0
0
0
% Q
% Arg:
10
10
0
10
0
0
0
0
0
0
10
0
0
0
19
% R
% Ser:
19
10
0
46
10
37
37
46
28
19
10
19
55
37
55
% S
% Thr:
0
0
37
10
10
0
0
10
0
0
0
10
0
10
10
% T
% Val:
0
10
10
0
0
10
37
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _