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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DMXL2
All Species:
12.12
Human Site:
T2280
Identified Species:
26.67
UniProt:
Q8TDJ6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDJ6
NP_056078.2
3036
339758
T2280
D
S
H
S
Y
S
Q
T
E
G
N
Q
F
T
G
Chimpanzee
Pan troglodytes
XP_510406
3036
339748
T2280
D
S
H
S
Y
S
Q
T
E
G
N
Q
F
T
G
Rhesus Macaque
Macaca mulatta
XP_001087241
3025
337728
F2255
G
S
H
N
Y
S
S
F
Q
T
N
Q
F
T
G
Dog
Lupus familis
XP_535481
3036
340032
Q2278
D
S
H
S
Y
S
S
Q
T
E
G
N
Q
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPN8
3032
338190
S2275
D
S
H
S
Y
S
Q
S
E
G
N
Q
F
T
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520974
2200
241353
A1533
R
K
A
A
L
K
N
A
F
S
L
L
G
K
Q
Chicken
Gallus gallus
XP_424958
2833
314679
G2166
L
K
T
K
T
D
D
G
E
K
Q
Q
K
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665441
3003
332749
M2248
E
A
S
Q
F
T
G
M
V
Y
Q
G
L
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572302
3419
376907
V2601
C
D
S
E
S
F
V
V
N
N
S
A
F
N
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510431
2948
330673
S2250
D
I
D
Q
I
Y
S
S
M
L
N
L
A
P
K
Sea Urchin
Strong. purpuratus
XP_790747
3216
355082
S2419
D
S
D
S
F
S
A
S
I
G
K
S
K
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
56
95.5
N.A.
92.9
N.A.
N.A.
56.8
51.1
N.A.
70.4
N.A.
37.8
N.A.
31.2
39
Protein Similarity:
100
99.7
71.8
97.8
N.A.
96.4
N.A.
N.A.
62.8
66.3
N.A.
81.5
N.A.
55.7
N.A.
50.9
57.3
P-Site Identity:
100
100
60
40
N.A.
93.3
N.A.
N.A.
0
13.3
N.A.
0
N.A.
13.3
N.A.
13.3
33.3
P-Site Similarity:
100
100
73.3
40
N.A.
100
N.A.
N.A.
6.6
13.3
N.A.
26.6
N.A.
20
N.A.
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
0
10
10
0
0
0
10
10
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
55
10
19
0
0
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
10
0
0
0
0
37
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
19
10
0
10
10
0
0
0
46
10
0
% F
% Gly:
10
0
0
0
0
0
10
10
0
37
10
10
10
0
46
% G
% His:
0
0
46
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
10
0
0
10
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
0
19
0
10
0
10
0
0
0
10
10
0
19
10
10
% K
% Leu:
10
0
0
0
10
0
0
0
0
10
10
19
10
10
10
% L
% Met:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
10
10
46
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
19
0
0
28
10
10
0
19
46
10
0
10
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
55
19
46
10
55
28
28
0
10
10
10
0
0
10
% S
% Thr:
0
0
10
0
10
10
0
19
10
10
0
0
0
37
10
% T
% Val:
0
0
0
0
0
0
10
10
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
46
10
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _