KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DMXL2
All Species:
21.82
Human Site:
Y246
Identified Species:
48
UniProt:
Q8TDJ6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDJ6
NP_056078.2
3036
339758
Y246
S
W
R
K
T
S
K
Y
M
P
R
G
S
V
C
Chimpanzee
Pan troglodytes
XP_510406
3036
339748
Y246
S
W
R
K
T
S
K
Y
M
P
R
G
S
V
C
Rhesus Macaque
Macaca mulatta
XP_001087241
3025
337728
Y245
S
W
R
K
T
S
K
Y
M
P
R
A
S
V
C
Dog
Lupus familis
XP_535481
3036
340032
Y246
S
W
R
K
T
S
K
Y
M
P
R
G
S
V
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPN8
3032
338190
Y246
S
W
R
K
T
S
K
Y
M
P
R
G
S
V
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520974
2200
241353
Chicken
Gallus gallus
XP_424958
2833
314679
A216
N
V
P
P
H
A
N
A
L
C
H
F
H
I
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665441
3003
332749
M226
W
R
K
T
S
K
Y
M
P
K
G
S
V
C
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572302
3419
376907
Y269
V
W
R
K
T
S
K
Y
M
P
K
G
S
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510431
2948
330673
E251
I
F
Y
Q
N
G
T
E
H
T
E
P
E
F
I
Sea Urchin
Strong. purpuratus
XP_790747
3216
355082
T226
V
E
N
T
K
E
H
T
T
T
T
T
K
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
56
95.5
N.A.
92.9
N.A.
N.A.
56.8
51.1
N.A.
70.4
N.A.
37.8
N.A.
31.2
39
Protein Similarity:
100
99.7
71.8
97.8
N.A.
96.4
N.A.
N.A.
62.8
66.3
N.A.
81.5
N.A.
55.7
N.A.
50.9
57.3
P-Site Identity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
0
0
N.A.
0
N.A.
80
N.A.
0
0
P-Site Similarity:
100
100
93.3
100
N.A.
100
N.A.
N.A.
0
26.6
N.A.
13.3
N.A.
86.6
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
46
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
10
0
10
0
0
10
0
10
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
10
46
0
0
0
% G
% His:
0
0
0
0
10
0
10
0
10
0
10
0
10
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% I
% Lys:
0
0
10
55
10
10
55
0
0
10
10
0
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
55
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
10
0
10
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
10
10
0
0
0
0
10
55
0
10
0
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
55
0
0
0
0
0
0
0
46
0
0
10
0
% R
% Ser:
46
0
0
0
10
55
0
0
0
0
0
10
55
0
0
% S
% Thr:
0
0
0
19
55
0
10
10
10
19
10
10
0
0
0
% T
% Val:
19
10
0
0
0
0
0
0
0
0
0
0
10
55
0
% V
% Trp:
10
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
10
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _