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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACER1
All Species:
12.73
Human Site:
S111
Identified Species:
23.33
UniProt:
Q8TDN7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDN7
NP_597999.1
264
31095
S111
M
P
R
C
Y
F
P
S
F
L
G
G
N
R
S
Chimpanzee
Pan troglodytes
XP_524068
264
31091
S111
M
P
R
C
Y
F
P
S
F
L
R
G
S
R
S
Rhesus Macaque
Macaca mulatta
XP_001087211
264
31190
S111
M
P
R
C
Y
F
P
S
F
L
G
G
N
R
S
Dog
Lupus familis
XP_854540
263
31141
T111
M
P
R
C
Y
F
P
T
F
L
G
E
N
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4X1
273
32063
K120
L
P
R
C
Y
F
P
K
F
V
K
G
N
R
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418208
263
31100
P110
W
Y
P
R
A
H
F
P
K
C
I
K
S
R
K
Frog
Xenopus laevis
NP_001090322
275
31185
R116
F
P
K
R
H
L
P
R
V
F
R
N
D
R
W
Zebra Danio
Brachydanio rerio
Q568I2
266
30890
P110
W
F
P
R
K
H
F
P
S
F
V
K
D
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIP7
283
32774
K126
Y
P
K
R
Y
Y
P
K
F
V
K
N
D
R
K
Honey Bee
Apis mellifera
XP_623814
269
30990
N111
L
P
R
R
Y
F
P
N
I
L
H
N
D
R
K
Nematode Worm
Caenorhab. elegans
O45145
272
31143
E118
P
V
M
K
W
F
P
E
K
F
S
K
R
L
T
Sea Urchin
Strong. purpuratus
XP_799207
298
34491
A141
Y
P
R
R
Y
Y
P
A
N
I
K
G
S
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38298
316
36401
I136
K
V
P
L
F
E
Q
I
F
I
G
V
I
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
96.2
85.2
N.A.
77.2
N.A.
N.A.
N.A.
47.3
37
48.5
N.A.
35.3
36.7
30.1
34.2
Protein Similarity:
100
98.8
98.8
92.8
N.A.
86.4
N.A.
N.A.
N.A.
68.1
57.4
73.3
N.A.
58.6
59.1
52.9
54.7
P-Site Identity:
100
86.6
100
80
N.A.
66.6
N.A.
N.A.
N.A.
6.6
20
6.6
N.A.
33.3
46.6
13.3
40
P-Site Similarity:
100
93.3
100
86.6
N.A.
80
N.A.
N.A.
N.A.
13.3
40
20
N.A.
60
66.6
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
39
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% D
% Glu:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% E
% Phe:
8
8
0
0
8
54
16
0
54
24
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
31
39
0
0
8
% G
% His:
0
0
0
0
8
16
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
8
16
8
0
8
8
0
% I
% Lys:
8
0
16
8
8
0
0
16
16
0
24
24
0
0
31
% K
% Leu:
16
0
0
8
0
8
0
0
0
39
0
0
0
8
0
% L
% Met:
31
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
24
31
0
0
% N
% Pro:
8
70
24
0
0
0
77
16
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
54
47
0
0
0
8
0
0
16
0
8
85
0
% R
% Ser:
0
0
0
0
0
0
0
24
8
0
8
0
24
0
24
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
16
% T
% Val:
0
16
0
0
0
0
0
0
8
16
8
8
0
0
0
% V
% Trp:
16
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
16
8
0
0
62
16
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _