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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACER1 All Species: 17.88
Human Site: S165 Identified Species: 32.78
UniProt: Q8TDN7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDN7 NP_597999.1 264 31095 S165 C Q E Y R K T S N K E L R H L
Chimpanzee Pan troglodytes XP_524068 264 31091 S165 C Q E Y R K T S N K E L R H L
Rhesus Macaque Macaca mulatta XP_001087211 264 31190 S165 C Q E Y R K T S N K E L R H L
Dog Lupus familis XP_854540 263 31141 S165 F Q E Y K K T S N K E L R H I
Cat Felis silvestris
Mouse Mus musculus Q8R4X1 273 32063 R174 R T E Y K K I R D D D L R H L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418208 263 31100 N164 W R E L K K C N D Q R V H R M
Frog Xenopus laevis NP_001090322 275 31185 D170 I A E L K R C D N M R V Y K L
Zebra Danio Brachydanio rerio Q568I2 266 30890 T164 F V E L K S C T D E R V L R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIP7 283 32774 S180 Y T E L Q R V S D Q R V Y R L
Honey Bee Apis mellifera XP_623814 269 30990 K165 I I E L K R T K S M R V Y R L
Nematode Worm Caenorhab. elegans O45145 272 31143 G172 N Y E G K Q S G I P D I E S F
Sea Urchin Strong. purpuratus XP_799207 298 34491 H195 V L E L R R A H C P R V V K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38298 316 36401 A190 R Y V H D P L A K R N L K A S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 96.2 85.2 N.A. 77.2 N.A. N.A. N.A. 47.3 37 48.5 N.A. 35.3 36.7 30.1 34.2
Protein Similarity: 100 98.8 98.8 92.8 N.A. 86.4 N.A. N.A. N.A. 68.1 57.4 73.3 N.A. 58.6 59.1 52.9 54.7
P-Site Identity: 100 100 100 80 N.A. 46.6 N.A. N.A. N.A. 13.3 20 13.3 N.A. 20 20 6.6 20
P-Site Similarity: 100 100 100 93.3 N.A. 66.6 N.A. N.A. N.A. 60 40 46.6 N.A. 53.3 46.6 40 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 8 8 0 0 0 0 0 8 0 % A
% Cys: 24 0 0 0 0 0 24 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 8 31 8 16 0 0 0 0 % D
% Glu: 0 0 93 0 0 0 0 0 0 8 31 0 8 0 0 % E
% Phe: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 8 0 0 0 0 8 39 0 % H
% Ile: 16 8 0 0 0 0 8 0 8 0 0 8 0 0 8 % I
% Lys: 0 0 0 0 54 47 0 8 8 31 0 0 8 16 0 % K
% Leu: 0 8 0 47 0 0 8 0 0 0 0 47 8 0 70 % L
% Met: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 8 % M
% Asn: 8 0 0 0 0 0 0 8 39 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 16 0 0 0 0 0 % P
% Gln: 0 31 0 0 8 8 0 0 0 16 0 0 0 0 0 % Q
% Arg: 16 8 0 0 31 31 0 8 0 8 47 0 39 31 0 % R
% Ser: 0 0 0 0 0 8 8 39 8 0 0 0 0 8 8 % S
% Thr: 0 16 0 0 0 0 39 8 0 0 0 0 0 0 0 % T
% Val: 8 8 8 0 0 0 8 0 0 0 0 47 8 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 16 0 39 0 0 0 0 0 0 0 0 24 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _