KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACER1
All Species:
16.06
Human Site:
Y21
Identified Species:
29.44
UniProt:
Q8TDN7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDN7
NP_597999.1
264
31095
Y21
W
C
E
S
N
F
Q
Y
S
E
L
V
A
E
F
Chimpanzee
Pan troglodytes
XP_524068
264
31091
Y21
W
C
E
S
N
F
Q
Y
S
E
L
V
A
E
F
Rhesus Macaque
Macaca mulatta
XP_001087211
264
31190
Y21
W
C
E
S
N
F
Q
Y
S
E
L
V
A
E
F
Dog
Lupus familis
XP_854540
263
31141
Y21
W
C
E
S
N
F
Q
Y
S
E
L
V
A
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4X1
273
32063
H30
W
C
E
S
N
F
Q
H
S
E
L
V
A
E
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418208
263
31100
R21
W
C
E
N
N
F
V
R
S
P
I
I
A
E
Y
Frog
Xenopus laevis
NP_001090322
275
31185
I26
W
C
E
D
N
Y
T
I
V
S
S
I
A
E
F
Zebra Danio
Brachydanio rerio
Q568I2
266
30890
H21
W
C
E
D
N
Y
K
H
S
E
N
V
V
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIP7
283
32774
I36
W
C
E
G
N
Y
L
I
S
S
N
I
A
E
F
Honey Bee
Apis mellifera
XP_623814
269
30990
I21
W
C
E
R
N
Y
S
I
S
S
S
I
A
E
F
Nematode Worm
Caenorhab. elegans
O45145
272
31143
Y25
W
C
E
S
A
Y
K
Y
Q
T
L
P
Y
V
A
Sea Urchin
Strong. purpuratus
XP_799207
298
34491
I51
W
C
E
N
N
Y
A
I
V
P
G
I
A
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38298
316
36401
V33
W
C
E
E
N
Y
V
V
S
P
Y
I
A
E
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
96.2
85.2
N.A.
77.2
N.A.
N.A.
N.A.
47.3
37
48.5
N.A.
35.3
36.7
30.1
34.2
Protein Similarity:
100
98.8
98.8
92.8
N.A.
86.4
N.A.
N.A.
N.A.
68.1
57.4
73.3
N.A.
58.6
59.1
52.9
54.7
P-Site Identity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
N.A.
53.3
46.6
53.3
N.A.
53.3
53.3
40
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
80
60
80
N.A.
66.6
66.6
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
0
0
0
0
85
0
8
% A
% Cys:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
100
8
0
0
0
0
0
47
0
0
0
93
0
% E
% Phe:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
70
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
31
0
0
8
47
0
0
0
% I
% Lys:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
47
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
93
0
0
0
0
0
16
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
24
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
39
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
47
0
0
8
0
77
24
16
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
16
8
16
0
0
47
8
8
0
% V
% Trp:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
54
0
39
0
0
8
0
8
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _