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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACER1 All Species: 30.61
Human Site: Y242 Identified Species: 56.11
UniProt: Q8TDN7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDN7 NP_597999.1 264 31095 Y242 G E T L K V R Y W P R D S W P
Chimpanzee Pan troglodytes XP_524068 264 31091 Y242 G E T L K V R Y W P R D S W P
Rhesus Macaque Macaca mulatta XP_001087211 264 31190 Y242 G E T L K V R Y W P R D N W P
Dog Lupus familis XP_854540 263 31141 Y242 G H T L K V R Y W P R D T W P
Cat Felis silvestris
Mouse Mus musculus Q8R4X1 273 32063 Y251 D K T L K V H Y W P R D S W V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418208 263 31100 Y241 A F K P K L G Y W P S D S W P
Frog Xenopus laevis NP_001090322 275 31185 F247 E Q G P V I R F W P S E K W A
Zebra Danio Brachydanio rerio Q568I2 266 30890 Y241 Y S L P D L Q Y W P R N N W A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIP7 283 32774 Y257 Q R Q P L L K Y W P K N E F E
Honey Bee Apis mellifera XP_623814 269 30990 Y242 Q Q S P V L K Y W P K D D F E
Nematode Worm Caenorhab. elegans O45145 272 31143 V249 T H K Y T A A V R Y F P G K N
Sea Urchin Strong. purpuratus XP_799207 298 34491 Y272 E M G P V L K Y W P K D S W V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38298 316 36401 L267 E H L R V I T L N V S C N Y Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 96.2 85.2 N.A. 77.2 N.A. N.A. N.A. 47.3 37 48.5 N.A. 35.3 36.7 30.1 34.2
Protein Similarity: 100 98.8 98.8 92.8 N.A. 86.4 N.A. N.A. N.A. 68.1 57.4 73.3 N.A. 58.6 59.1 52.9 54.7
P-Site Identity: 100 100 93.3 86.6 N.A. 73.3 N.A. N.A. N.A. 53.3 26.6 33.3 N.A. 20 26.6 0 40
P-Site Similarity: 100 100 100 93.3 N.A. 80 N.A. N.A. N.A. 60 53.3 60 N.A. 53.3 66.6 0 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 8 0 0 0 0 0 0 0 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 8 0 0 0 8 0 0 0 0 0 0 62 8 0 0 % D
% Glu: 24 24 0 0 0 0 0 0 0 0 0 8 8 0 16 % E
% Phe: 0 8 0 0 0 0 0 8 0 0 8 0 0 16 0 % F
% Gly: 31 0 16 0 0 0 8 0 0 0 0 0 8 0 0 % G
% His: 0 24 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 16 0 47 0 24 0 0 0 24 0 8 8 0 % K
% Leu: 0 0 16 39 8 39 0 8 0 0 0 0 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 16 24 0 8 % N
% Pro: 0 0 0 47 0 0 0 0 0 85 0 8 0 0 39 % P
% Gln: 16 16 8 0 0 0 8 0 0 0 0 0 0 0 8 % Q
% Arg: 0 8 0 8 0 0 39 0 8 0 47 0 0 0 0 % R
% Ser: 0 8 8 0 0 0 0 0 0 0 24 0 39 0 0 % S
% Thr: 8 0 39 0 8 0 8 0 0 0 0 0 8 0 0 % T
% Val: 0 0 0 0 31 39 0 8 0 8 0 0 0 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 85 0 0 0 0 70 0 % W
% Tyr: 8 0 0 8 0 0 0 77 0 8 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _