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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACER1
All Species:
26.06
Human Site:
Y254
Identified Species:
47.78
UniProt:
Q8TDN7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDN7
NP_597999.1
264
31095
Y254
S
W
P
V
G
L
P
Y
V
E
I
R
G
D
D
Chimpanzee
Pan troglodytes
XP_524068
264
31091
Y254
S
W
P
V
G
L
P
Y
V
E
I
R
G
D
D
Rhesus Macaque
Macaca mulatta
XP_001087211
264
31190
Y254
N
W
P
V
G
L
P
Y
V
E
I
R
G
D
D
Dog
Lupus familis
XP_854540
263
31141
Y254
T
W
P
V
G
L
P
Y
V
E
V
S
D
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R4X1
273
32063
Y263
S
W
V
I
G
L
P
Y
V
E
I
Q
E
N
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418208
263
31100
Y253
S
W
P
I
V
V
P
Y
I
A
L
E
D
P
H
Frog
Xenopus laevis
NP_001090322
275
31185
P259
K
W
A
F
I
G
V
P
Y
V
T
L
L
C
A
Zebra Danio
Brachydanio rerio
Q568I2
266
30890
Y253
N
W
A
I
G
L
P
Y
I
V
L
K
G
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIP7
283
32774
F269
E
F
E
F
G
I
P
F
I
S
I
R
N
P
G
Honey Bee
Apis mellifera
XP_623814
269
30990
Y254
D
F
E
L
G
I
P
Y
V
T
I
R
S
Y
V
Nematode Worm
Caenorhab. elegans
O45145
272
31143
S261
G
K
N
G
S
I
F
S
F
P
Y
I
S
L
K
Sea Urchin
Strong. purpuratus
XP_799207
298
34491
P284
S
W
V
N
A
G
I
P
Y
V
N
L
Q
C
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38298
316
36401
W279
N
Y
Q
F
I
W
R
W
K
V
F
P
E
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
96.2
85.2
N.A.
77.2
N.A.
N.A.
N.A.
47.3
37
48.5
N.A.
35.3
36.7
30.1
34.2
Protein Similarity:
100
98.8
98.8
92.8
N.A.
86.4
N.A.
N.A.
N.A.
68.1
57.4
73.3
N.A.
58.6
59.1
52.9
54.7
P-Site Identity:
100
100
93.3
60
N.A.
66.6
N.A.
N.A.
N.A.
33.3
6.6
40
N.A.
26.6
40
0
13.3
P-Site Similarity:
100
100
100
80
N.A.
86.6
N.A.
N.A.
N.A.
60
6.6
80
N.A.
53.3
60
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
8
0
0
0
0
8
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
16
24
31
% D
% Glu:
8
0
16
0
0
0
0
0
0
39
0
8
16
0
0
% E
% Phe:
0
16
0
24
0
0
8
8
8
0
8
0
0
0
0
% F
% Gly:
8
0
0
8
62
16
0
0
0
0
0
0
31
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
24
16
24
8
0
24
0
47
8
0
0
8
% I
% Lys:
8
8
0
0
0
0
0
0
8
0
0
8
0
0
16
% K
% Leu:
0
0
0
8
0
47
0
0
0
0
16
16
8
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
24
0
8
8
0
0
0
0
0
0
8
0
8
16
8
% N
% Pro:
0
0
39
0
0
0
70
16
0
8
0
8
0
16
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
8
8
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
39
0
0
0
% R
% Ser:
39
0
0
0
8
0
0
8
0
8
0
8
16
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
8
0
0
8
0
% T
% Val:
0
0
16
31
8
8
8
0
47
31
8
0
0
0
8
% V
% Trp:
0
70
0
0
0
8
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
62
16
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _