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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACER1 All Species: 34.24
Human Site: Y51 Identified Species: 62.78
UniProt: Q8TDN7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDN7 NP_597999.1 264 31095 Y51 M M L L M H P Y A Q K R S R Y
Chimpanzee Pan troglodytes XP_524068 264 31091 Y51 M M L L M H P Y A Q K R S R Y
Rhesus Macaque Macaca mulatta XP_001087211 264 31190 Y51 M M L L M H P Y A Q K R S R Y
Dog Lupus familis XP_854540 263 31141 Y51 M M F L M H P Y A Q K R S R Y
Cat Felis silvestris
Mouse Mus musculus Q8R4X1 273 32063 Y60 M M F L M H P Y A Q K R T R C
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418208 263 31100 Y51 L L H L N R Q Y C Q Q R T V P
Frog Xenopus laevis NP_001090322 275 31185 Y56 C M C L F R Q Y A T C F N S G
Zebra Danio Brachydanio rerio Q568I2 266 30890 Y51 M L Y L L H P Y A K E R N L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIP7 283 32774 Y66 L I M L F K E Y G R F V T P G
Honey Bee Apis mellifera XP_623814 269 30990 Y51 L M H L F R D Y G R F I N P G
Nematode Worm Caenorhab. elegans O45145 272 31143 Y57 N I M L L R R Y L H D V N G G
Sea Urchin Strong. purpuratus XP_799207 298 34491 Y81 L L Y L F R Q Y A V R Y N W H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38298 316 36401 Y61 I Y T T Y S A Y K N K L E K R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 96.2 85.2 N.A. 77.2 N.A. N.A. N.A. 47.3 37 48.5 N.A. 35.3 36.7 30.1 34.2
Protein Similarity: 100 98.8 98.8 92.8 N.A. 86.4 N.A. N.A. N.A. 68.1 57.4 73.3 N.A. 58.6 59.1 52.9 54.7
P-Site Identity: 100 100 100 93.3 N.A. 80 N.A. N.A. N.A. 26.6 26.6 46.6 N.A. 13.3 20 13.3 20
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 N.A. N.A. N.A. 53.3 33.3 80 N.A. 46.6 40 40 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 62 0 0 0 0 0 8 % A
% Cys: 8 0 8 0 0 0 0 0 8 0 8 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 8 0 8 0 0 % E
% Phe: 0 0 16 0 31 0 0 0 0 0 16 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 16 0 0 0 0 8 31 % G
% His: 0 0 16 0 0 47 0 0 0 8 0 0 0 0 8 % H
% Ile: 8 16 0 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 8 8 47 0 0 8 0 % K
% Leu: 31 24 24 93 16 0 0 0 8 0 0 8 0 8 0 % L
% Met: 47 54 16 0 39 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 0 0 0 8 0 0 39 0 0 % N
% Pro: 0 0 0 0 0 0 47 0 0 0 0 0 0 16 8 % P
% Gln: 0 0 0 0 0 0 24 0 0 47 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 39 8 0 0 16 8 54 0 39 8 % R
% Ser: 0 0 0 0 0 8 0 0 0 0 0 0 31 8 0 % S
% Thr: 0 0 8 8 0 0 0 0 0 8 0 0 24 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 8 0 16 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 8 16 0 8 0 0 100 0 0 0 8 0 0 31 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _