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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNASEH2C
All Species:
20
Human Site:
S62
Identified Species:
62.86
UniProt:
Q8TDP1
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDP1
NP_115569.2
164
17840
S62
G
P
E
G
L
E
V
S
F
R
G
R
C
L
R
Chimpanzee
Pan troglodytes
XP_508559
164
17823
S62
G
P
E
G
L
E
V
S
F
R
G
R
C
L
R
Rhesus Macaque
Macaca mulatta
XP_001085695
164
17721
S62
G
P
E
G
L
E
V
S
F
R
G
R
C
L
R
Dog
Lupus familis
XP_852826
168
18623
S62
G
P
D
G
L
E
V
S
F
R
G
R
K
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ18
166
17805
S62
D
A
D
G
L
Q
A
S
F
R
G
R
G
L
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001154849
137
15359
E49
F
F
N
P
T
V
K
E
R
K
H
E
T
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176091
151
16457
S56
G
T
T
G
Q
Q
V
S
F
R
G
R
L
L
R
Poplar Tree
Populus trichocarpa
XP_002332136
168
18347
H68
E
M
K
V
E
E
A
H
F
R
G
R
K
L
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
95.1
75
N.A.
65
N.A.
N.A.
N.A.
N.A.
N.A.
34.7
N.A.
N.A.
N.A.
N.A.
28
Protein Similarity:
100
100
96.3
82.1
N.A.
75.3
N.A.
N.A.
N.A.
N.A.
N.A.
51.8
N.A.
N.A.
N.A.
N.A.
39.6
P-Site Identity:
100
100
100
86.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
24.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
42.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
0
25
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
0
% C
% Asp:
13
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
13
0
38
0
13
63
0
13
0
0
0
13
0
0
0
% E
% Phe:
13
13
0
0
0
0
0
0
88
0
0
0
0
0
0
% F
% Gly:
63
0
0
75
0
0
0
0
0
0
88
0
13
0
0
% G
% His:
0
0
0
0
0
0
0
13
0
0
13
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
13
0
0
13
0
0
25
0
0
% K
% Leu:
0
0
0
0
63
0
0
0
0
0
0
0
13
88
0
% L
% Met:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
50
0
13
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
13
25
0
0
0
0
0
0
0
0
13
% Q
% Arg:
0
0
0
0
0
0
0
0
13
88
0
88
0
0
75
% R
% Ser:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% S
% Thr:
0
13
13
0
13
0
0
0
0
0
0
0
13
13
0
% T
% Val:
0
0
0
13
0
13
63
0
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _