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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAVCR2
All Species:
4.24
Human Site:
Y283
Identified Species:
13.33
UniProt:
Q8TDQ0
Number Species:
7
Phosphosite Substitution
Charge Score:
0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDQ0
NP_116171.3
301
33351
Y283
E
P
N
E
Y
Y
C
Y
V
S
S
R
Q
Q
P
Chimpanzee
Pan troglodytes
XP_518059
273
30052
Y255
E
P
N
E
Y
Y
C
Y
V
S
S
G
Q
Q
P
Rhesus Macaque
Macaca mulatta
XP_001104859
337
36773
L276
E
P
N
E
N
Y
G
L
C
Q
L
T
G
F
G
Dog
Lupus familis
XP_536456
469
53043
E454
E
E
N
I
Y
E
M
E
D
P
Y
E
Y
Y
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8VIM0
281
30916
E266
E
E
N
V
Y
E
V
E
N
S
N
E
Y
Y
C
Rat
Rattus norvegicus
P0C0K5
164
17749
H149
T
Q
T
L
V
T
L
H
D
N
N
G
T
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507438
441
48536
N388
I
F
K
W
H
I
H
N
R
K
K
M
Q
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116089
259
28997
E244
E
P
R
H
I
I
Y
E
I
R
T
R
R
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
74.1
41.5
N.A.
60.7
32.2
N.A.
22.2
N.A.
N.A.
24.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
89.3
78.3
48.6
N.A.
70
41.8
N.A.
35.1
N.A.
N.A.
41.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
33.3
20
N.A.
26.6
0
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
33.3
20
N.A.
33.3
26.6
N.A.
13.3
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
25
0
13
0
0
0
0
0
25
% C
% Asp:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% D
% Glu:
75
25
0
38
0
25
0
38
0
0
0
25
0
0
0
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
0
0
0
13
0
% F
% Gly:
0
0
0
0
0
0
13
0
0
0
0
25
13
0
13
% G
% His:
0
0
0
13
13
0
13
13
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
13
13
25
0
0
13
0
0
0
0
0
13
% I
% Lys:
0
0
13
0
0
0
0
0
0
13
13
0
0
13
0
% K
% Leu:
0
0
0
13
0
0
13
13
0
0
13
0
0
0
13
% L
% Met:
0
0
0
0
0
0
13
0
0
0
0
13
0
0
0
% M
% Asn:
0
0
63
0
13
0
0
13
13
13
25
0
0
0
0
% N
% Pro:
0
50
0
0
0
0
0
0
0
13
0
0
0
13
25
% P
% Gln:
0
13
0
0
0
0
0
0
0
13
0
0
38
25
0
% Q
% Arg:
0
0
13
0
0
0
0
0
13
13
0
25
13
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
38
25
0
0
13
0
% S
% Thr:
13
0
13
0
0
13
0
0
0
0
13
13
13
0
0
% T
% Val:
0
0
0
13
13
0
13
0
25
0
0
0
0
0
13
% V
% Trp:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
50
38
13
25
0
0
13
0
25
25
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _