KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNPDA2
All Species:
24.09
Human Site:
S271
Identified Species:
44.16
UniProt:
Q8TDQ7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDQ7
NP_612208.1
276
31085
S271
K
L
V
D
P
L
F
S
M
K
D
G
N
_
_
Chimpanzee
Pan troglodytes
XP_001143245
399
44550
S394
K
L
V
D
P
L
F
S
M
K
D
G
N
_
_
Rhesus Macaque
Macaca mulatta
XP_001091343
361
40474
S343
K
L
V
D
P
L
Y
S
I
K
E
K
E
T
E
Dog
Lupus familis
XP_849417
276
31118
S271
K
L
V
D
P
L
Y
S
M
K
E
G
N
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9CRC9
276
31065
S271
K
L
V
D
P
L
Y
S
M
K
E
G
N
_
_
Rat
Rattus norvegicus
NP_001099475
276
30988
S271
K
L
V
D
P
L
C
S
M
K
E
G
D
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420726
275
31117
Frog
Xenopus laevis
Q6PA43
275
30901
Zebra Danio
Brachydanio rerio
XP_684147
277
31333
S271
Q
L
V
E
P
T
L
S
V
K
D
Y
M
D
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMP9
273
30806
Honey Bee
Apis mellifera
XP_393026
279
31676
N271
K
L
I
E
E
D
G
N
T
I
L
R
R
S
V
Nematode Worm
Caenorhab. elegans
Q9XVJ2
267
29895
F254
K
V
K
T
V
K
Y
F
K
G
L
M
N
H
H
Sea Urchin
Strong. purpuratus
XP_790227
281
32124
E271
K
L
V
E
D
S
K
E
L
P
E
V
K
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.1
65.3
98.1
N.A.
97
97
N.A.
N.A.
94.5
93.1
86.6
N.A.
73.9
74.9
65.2
76.5
Protein Similarity:
100
69.1
70.3
98.9
N.A.
99.6
99.2
N.A.
N.A.
96.7
96.3
93.5
N.A.
85.1
84.2
79.3
86.4
P-Site Identity:
100
100
53.3
84.6
N.A.
84.6
76.9
N.A.
N.A.
0
0
42.8
N.A.
0
13.3
13.3
20
P-Site Similarity:
100
100
73.3
100
N.A.
100
92.3
N.A.
N.A.
0
0
64.2
N.A.
0
33.3
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
47
8
8
0
0
0
0
24
0
8
8
0
% D
% Glu:
0
0
0
24
8
0
0
8
0
0
39
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
16
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
8
0
39
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
70
0
8
0
0
8
8
0
8
54
0
8
8
0
0
% K
% Leu:
0
70
0
0
0
47
8
0
8
0
16
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
39
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
39
0
0
% N
% Pro:
0
0
0
0
54
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% R
% Ser:
0
0
0
0
0
8
0
54
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
8
0
8
0
0
8
0
0
0
0
8
0
% T
% Val:
0
8
62
0
8
0
0
0
8
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
31
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
47
% _