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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNPDA2 All Species: 47.27
Human Site: Y34 Identified Species: 86.67
UniProt: Q8TDQ7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDQ7 NP_612208.1 276 31085 Y34 F K P G Q D R Y F T L G L P T
Chimpanzee Pan troglodytes XP_001143245 399 44550 Y157 F K P G Q D R Y F T L G L P T
Rhesus Macaque Macaca mulatta XP_001091343 361 40474 Y114 F N P G P E K Y F T L G L P T
Dog Lupus familis XP_849417 276 31118 Y34 F K P G Q D R Y F T L G L P T
Cat Felis silvestris
Mouse Mus musculus Q9CRC9 276 31065 Y34 F K P G Q D R Y F S L G L P T
Rat Rattus norvegicus NP_001099475 276 30988 Y34 F K P G Q D R Y F S L G L P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420726 275 31117 Y34 F K P T Q G R Y F T L G L P T
Frog Xenopus laevis Q6PA43 275 30901 Y34 F N P G P D K Y F T L G L P T
Zebra Danio Brachydanio rerio XP_684147 277 31333 Y34 F K P S A D R Y F T L G L P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VMP9 273 30806 Y34 F Q P S A D R Y F V L G L P T
Honey Bee Apis mellifera XP_393026 279 31676 Y34 F Q P N E N K Y F I L G L P T
Nematode Worm Caenorhab. elegans Q9XVJ2 267 29895 Y33 E A T E N G K Y L V L G L P T
Sea Urchin Strong. purpuratus XP_790227 281 32124 Y34 F S P T K D K Y F V L G L P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.1 65.3 98.1 N.A. 97 97 N.A. N.A. 94.5 93.1 86.6 N.A. 73.9 74.9 65.2 76.5
Protein Similarity: 100 69.1 70.3 98.9 N.A. 99.6 99.2 N.A. N.A. 96.7 96.3 93.5 N.A. 85.1 84.2 79.3 86.4
P-Site Identity: 100 100 73.3 100 N.A. 93.3 93.3 N.A. N.A. 86.6 80 86.6 N.A. 73.3 60 40 66.6
P-Site Similarity: 100 100 86.6 100 N.A. 100 100 N.A. N.A. 86.6 86.6 86.6 N.A. 80 86.6 46.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 16 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 8 8 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 93 0 0 0 0 0 0 0 93 0 0 0 0 0 0 % F
% Gly: 0 0 0 54 0 16 0 0 0 0 0 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 54 0 0 8 0 39 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 8 0 100 0 100 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 16 0 8 8 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 93 0 16 0 0 0 0 0 0 0 0 100 0 % P
% Gln: 0 16 0 0 47 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 62 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 16 0 0 0 0 0 16 0 0 0 0 0 % S
% Thr: 0 0 8 16 0 0 0 0 0 54 0 0 0 0 100 % T
% Val: 0 0 0 0 0 0 0 0 0 24 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _