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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR109A
All Species:
12.38
Human Site:
Y357
Identified Species:
30.26
UniProt:
Q8TDS4
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDS4
NP_808219.1
363
41850
Y357
G
E
P
W
S
P
S
Y
L
G
P
T
S
P
_
Chimpanzee
Pan troglodytes
XP_509519
387
44469
Y357
G
E
P
W
S
P
S
Y
L
G
P
T
S
N
N
Rhesus Macaque
Macaca mulatta
XP_001110986
423
45736
Dog
Lupus familis
XP_543378
363
42072
Y357
G
E
P
R
N
P
S
Y
L
T
P
A
S
R
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP66
360
41382
Y354
S
E
P
G
S
P
P
Y
L
A
S
T
S
R
_
Rat
Rattus norvegicus
Q80Z39
360
41440
Y354
S
E
P
G
S
P
P
Y
L
A
S
T
S
R
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506828
616
69877
P602
P
D
V
L
L
T
N
P
E
R
T
W
S
T
S
Chicken
Gallus gallus
P34996
362
41176
Q356
N
I
L
T
E
Y
K
Q
N
G
D
T
S
L
_
Frog
Xenopus laevis
P79928
537
62006
G471
I
D
S
R
L
K
R
G
K
W
Q
L
S
S
K
Zebra Danio
Brachydanio rerio
NP_001156767
310
35962
L304
R
K
I
Y
M
R
M
L
G
Q
K
I
E
E
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.6
30.9
86.2
N.A.
81.5
82.3
N.A.
44.1
27.5
20.6
38.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
91.2
46.8
92.2
N.A.
87.3
87.8
N.A.
49.5
47.9
36.8
55.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
0
64.2
N.A.
57.1
57.1
N.A.
6.6
21.4
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
0
71.4
N.A.
57.1
57.1
N.A.
20
21.4
13.3
14.2
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
20
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
50
0
0
10
0
0
0
10
0
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
30
0
0
20
0
0
0
10
10
30
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
10
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
10
0
0
0
10
10
0
10
0
10
0
0
0
10
% K
% Leu:
0
0
10
10
20
0
0
10
50
0
0
10
0
10
0
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
0
10
0
10
0
0
0
0
10
10
% N
% Pro:
10
0
50
0
0
50
20
10
0
0
30
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% Q
% Arg:
10
0
0
20
0
10
10
0
0
10
0
0
0
30
0
% R
% Ser:
20
0
10
0
40
0
30
0
0
0
20
0
80
10
10
% S
% Thr:
0
0
0
10
0
10
0
0
0
10
10
50
0
10
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
20
0
0
0
0
0
10
0
10
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% _