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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPBAR1
All Species:
0.91
Human Site:
S307
Identified Species:
2.86
UniProt:
Q8TDU6
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDU6
NP_001070659.1
330
35248
S307
Q
G
L
W
G
R
A
S
R
D
S
P
G
P
S
Chimpanzee
Pan troglodytes
Q9TUK4
317
34681
P295
I
C
N
A
I
I
D
P
L
I
Y
A
F
H
S
Rhesus Macaque
Macaca mulatta
Q864J4
317
34745
I292
A
L
I
I
C
N
A
I
I
D
P
L
I
Y
A
Dog
Lupus familis
XP_545641
330
34947
P307
Q
G
L
Q
G
R
A
P
R
G
G
P
G
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80SS6
329
35632
K306
R
V
L
R
G
R
A
K
R
D
N
P
G
P
S
Rat
Rattus norvegicus
Q80T02
329
35773
K306
Q
V
L
R
G
R
P
K
R
A
N
P
G
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087918
258
30149
T236
Y
C
C
K
R
R
E
T
L
S
N
L
H
D
M
Zebra Danio
Brachydanio rerio
XP_001337646
271
31259
I249
N
K
Q
Y
T
E
P
I
R
R
V
M
L
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.3
24.5
88.4
N.A.
82.1
82.1
N.A.
N.A.
N.A.
28.4
24.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
35.1
36.6
91.5
N.A.
88.4
87.5
N.A.
N.A.
N.A.
44.2
40.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
13.3
66.6
N.A.
66.6
60
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
26.6
66.6
N.A.
80
66.6
N.A.
N.A.
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
13
0
0
50
0
0
13
0
13
0
0
13
% A
% Cys:
0
25
13
0
13
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
13
0
0
38
0
0
0
13
0
% D
% Glu:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% F
% Gly:
0
25
0
0
50
0
0
0
0
13
13
0
50
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
13
0
% H
% Ile:
13
0
13
13
13
13
0
25
13
13
0
0
13
0
0
% I
% Lys:
0
13
0
13
0
0
0
25
0
0
0
0
0
13
0
% K
% Leu:
0
13
50
0
0
0
0
0
25
0
0
25
13
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
13
% M
% Asn:
13
0
13
0
0
13
0
0
0
0
38
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
25
25
0
0
13
50
0
50
0
% P
% Gln:
38
0
13
13
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
0
25
13
63
0
0
63
13
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
13
0
13
13
0
0
0
50
% S
% Thr:
0
0
0
0
13
0
0
13
0
0
0
0
0
0
0
% T
% Val:
0
25
0
0
0
0
0
0
0
0
13
0
0
0
0
% V
% Trp:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
13
0
0
0
0
0
0
13
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _