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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACMSD
All Species:
29.7
Human Site:
Y23
Identified Species:
72.59
UniProt:
Q8TDX5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDX5
NP_612199.2
336
38035
Y23
D
L
K
K
R
F
G
Y
G
G
W
V
Q
L
Q
Chimpanzee
Pan troglodytes
XP_515804
336
37989
Y23
D
L
K
K
R
F
G
Y
G
G
W
V
Q
L
Q
Rhesus Macaque
Macaca mulatta
XP_001097996
336
38133
Y23
D
L
K
K
R
F
G
Y
E
G
W
V
Q
L
Q
Dog
Lupus familis
XP_533332
308
34482
K23
A
K
M
L
K
D
G
K
V
F
R
V
V
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R519
336
38009
Y23
D
L
E
K
R
F
G
Y
G
G
W
V
Q
L
Q
Rat
Rattus norvegicus
Q8R5M5
336
38073
Y23
D
L
E
K
R
F
G
Y
G
G
W
V
Q
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422133
336
38160
Y23
D
L
K
K
R
Y
G
Y
D
G
W
V
Q
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001082963
336
37964
Y23
D
L
K
Q
R
Y
G
Y
G
G
F
V
Q
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8T8B9
401
45728
Y35
D
F
Q
E
K
F
G
Y
P
G
F
V
R
L
D
Sea Urchin
Strong. purpuratus
XP_001190504
318
35162
G50
K
H
P
K
R
F
V
G
L
G
T
L
P
M
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.2
78.5
N.A.
87.1
86
N.A.
N.A.
80.6
N.A.
81.2
N.A.
N.A.
N.A.
43.6
57.4
Protein Similarity:
100
99.6
99.1
86.9
N.A.
94.9
93.7
N.A.
N.A.
91.6
N.A.
91.6
N.A.
N.A.
N.A.
59.5
70.8
P-Site Identity:
100
100
93.3
13.3
N.A.
93.3
93.3
N.A.
N.A.
80
N.A.
73.3
N.A.
N.A.
N.A.
46.6
33.3
P-Site Similarity:
100
100
93.3
26.6
N.A.
100
100
N.A.
N.A.
86.6
N.A.
93.3
N.A.
N.A.
N.A.
80
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
80
0
0
0
0
10
0
0
10
0
0
0
0
0
20
% D
% Glu:
0
0
20
10
0
0
0
0
10
0
0
0
0
0
10
% E
% Phe:
0
10
0
0
0
70
0
0
0
10
20
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
90
10
50
90
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
50
70
20
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
0
70
0
10
0
0
0
0
10
0
0
10
0
80
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
10
0
0
0
10
0
0
% P
% Gln:
0
0
10
10
0
0
0
0
0
0
0
0
70
10
60
% Q
% Arg:
0
0
0
0
80
0
0
0
0
0
10
0
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
10
0
0
90
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% W
% Tyr:
0
0
0
0
0
20
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _