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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MICAL1
All Species:
13.03
Human Site:
T446
Identified Species:
35.83
UniProt:
Q8TDZ2
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDZ2
NP_001152763.1
1067
117875
T446
L
Y
Q
L
L
S
Q
T
S
P
E
N
M
H
R
Chimpanzee
Pan troglodytes
XP_001153132
1067
117837
T446
L
Y
Q
L
L
S
Q
T
S
P
E
N
M
H
R
Rhesus Macaque
Macaca mulatta
XP_001090339
1066
117658
T446
L
Y
Q
L
L
S
Q
T
S
P
E
N
M
H
R
Dog
Lupus familis
XP_539079
1074
116934
L487
R
E
S
L
Y
Q
L
L
S
Q
T
S
P
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDP3
1048
116766
Q445
S
L
Y
Q
L
L
S
Q
T
S
P
E
N
M
H
Rat
Rattus norvegicus
NP_001099867
1047
116653
E437
L
E
L
L
A
E
R
E
S
L
Y
Q
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516246
1901
212286
N455
L
P
Q
T
T
P
E
N
V
S
K
N
F
S
H
Chicken
Gallus gallus
NP_001026747
1142
128140
T449
I
Y
Q
H
L
S
Q
T
S
P
D
N
T
N
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922250
1499
169833
E454
L
L
P
Q
T
T
A
E
N
I
S
K
N
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.7
72.1
N.A.
79.5
78
N.A.
30.3
52.3
N.A.
33.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
97.5
78.9
N.A.
87.2
85.8
N.A.
40.1
64.5
N.A.
46.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
6.6
20
N.A.
20
60
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
13.3
33.3
N.A.
33.3
86.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% D
% Glu:
0
23
0
0
0
12
12
23
0
0
34
12
0
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
34
23
% H
% Ile:
12
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
12
% K
% Leu:
67
23
12
56
56
12
12
12
0
12
0
0
12
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
34
12
0
% M
% Asn:
0
0
0
0
0
0
0
12
12
0
0
56
23
12
12
% N
% Pro:
0
12
12
0
0
12
0
0
0
45
12
0
12
0
0
% P
% Gln:
0
0
56
23
0
12
45
12
0
12
0
12
0
0
0
% Q
% Arg:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
34
% R
% Ser:
12
0
12
0
0
45
12
0
67
23
12
12
0
12
12
% S
% Thr:
0
0
0
12
23
12
0
45
12
0
12
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
45
12
0
12
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _