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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DERP6
All Species:
18.18
Human Site:
S259
Identified Species:
50
UniProt:
Q8TE02
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE02
NP_056177.3
316
34841
S259
L
T
F
N
L
H
L
S
K
K
E
R
E
A
R
Chimpanzee
Pan troglodytes
XP_001172407
316
34819
S259
L
T
F
N
L
H
L
S
K
K
E
R
E
A
R
Rhesus Macaque
Macaca mulatta
XP_001118001
376
40884
S319
L
T
F
N
L
H
L
S
K
K
E
R
E
A
R
Dog
Lupus familis
XP_536617
338
36867
S281
L
T
F
N
L
N
L
S
K
K
E
R
E
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99L85
300
33479
R250
S
K
K
E
R
E
A
R
D
S
L
T
L
P
F
Rat
Rattus norvegicus
Q6IUP3
318
35472
S261
L
T
F
N
L
H
L
S
K
K
E
R
E
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520446
191
20252
L141
P
L
G
S
L
A
H
L
A
V
A
E
V
T
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1A5V9
296
32720
R245
L
R
L
S
E
E
E
R
R
A
K
E
K
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201841
293
32640
L243
N
L
T
F
N
L
T
L
S
E
S
E
K
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
81.3
73.9
N.A.
71.8
72.6
N.A.
23.1
N.A.
N.A.
34.8
N.A.
N.A.
N.A.
N.A.
25
Protein Similarity:
100
99
81.9
80.4
N.A.
79.4
79.8
N.A.
33.2
N.A.
N.A.
53.1
N.A.
N.A.
N.A.
N.A.
43.6
P-Site Identity:
100
100
100
86.6
N.A.
0
93.3
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
0
100
N.A.
13.3
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
12
0
12
12
12
0
0
56
23
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
0
12
12
23
12
0
0
12
56
34
56
0
0
% E
% Phe:
0
0
56
12
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
45
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
12
0
0
0
0
0
56
56
12
0
23
12
23
% K
% Leu:
67
23
12
0
67
12
56
23
0
0
12
0
12
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
56
12
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
12
0
0
23
12
0
0
56
0
0
34
% R
% Ser:
12
0
0
23
0
0
0
56
12
12
12
0
0
0
0
% S
% Thr:
0
56
12
0
0
0
12
0
0
0
0
12
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
0
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _