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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAS1R2 All Species: 10.3
Human Site: S727 Identified Species: 25.19
UniProt: Q8TE23 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TE23 NP_689418.2 839 95183 S727 C N P N Y R N S L L F N T S L
Chimpanzee Pan troglodytes A3QNZ8 839 95029 S727 C N P N Y R N S L L F N T S L
Rhesus Macaque Macaca mulatta A3QP01 839 95041 S727 C N P N Y R N S L F F N T G L
Dog Lupus familis XP_855275 836 95049 A724 L S C N Y R R A L L F N T S L
Cat Felis silvestris
Mouse Mus musculus Q925I4 843 95717 G731 C H P N Y R N G L L F N T S M
Rat Rattus norvegicus Q9Z0R7 843 95781 G731 C H P N Y R N G L L F N T S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519301 381 42904 A269 C D P N Y R H A L L S N T G M
Chicken Gallus gallus XP_425734 725 78917 T614 A G S A P G E T A A I L Y N L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U9X3 867 97118 G727 V M F W L M L G Y I A L L A L
Tiger Blowfish Takifugu rubipres NP_001098687 824 92009 S713 F M N L K T S S G S T V L L L
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 92 76.5 N.A. 69.5 70.8 N.A. 30.9 29 N.A. 27.2 32.9 N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 95.7 84.3 N.A. 82.8 83.6 N.A. 36.8 44.3 N.A. 48.2 52.4 N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 66.6 N.A. 80 80 N.A. 60 6.6 N.A. 6.6 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 80 N.A. 93.3 93.3 N.A. 86.6 20 N.A. 20 20 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 20 10 10 10 0 0 10 0 % A
% Cys: 60 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 10 0 0 0 0 0 0 10 60 0 0 0 0 % F
% Gly: 0 10 0 0 0 10 0 30 10 0 0 0 0 20 0 % G
% His: 0 20 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 10 10 0 10 0 70 60 0 20 20 10 70 % L
% Met: 0 20 0 0 0 10 0 0 0 0 0 0 0 0 30 % M
% Asn: 0 30 10 70 0 0 50 0 0 0 0 70 0 10 0 % N
% Pro: 0 0 60 0 10 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 70 10 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 10 0 0 0 10 40 0 10 10 0 0 50 0 % S
% Thr: 0 0 0 0 0 10 0 10 0 0 10 0 70 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 70 0 0 0 10 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _